| Literature DB >> 15146189 |
Fabrizio Benedetti1, Luana Colloca, Elena Torre, Michele Lanotte, Antonio Melcarne, Marina Pesare, Bruno Bergamasco, Leonardo Lopiano.
Abstract
Placebo administration is known to affect the brain both in pain and in Parkinson disease. Here we show that placebo treatment caused reduced activity in single neurons in the subthalamic nucleus of placebo-responsive Parkinsonian patients. These changes in activity were tightly correlated with clinical improvement; no decrease in activity occurred when the clinical placebo response was absent.Entities:
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Year: 2004 PMID： 15146189 DOI： 10.1038/nn1250
Source DB: PubMed Journal: Nat Neurosci ISSN： 1097-6256 Impact factor: 24.884