OBJECTIVE: To investigate the role of cardiovascular magnetic resonance (CMR) in a series of patients with ECG repolarisation changes and normal echocardiography. PATIENTS AND DESIGN: 10 patients with anterolateral T wave inversion for which there was no obvious pathological cause who had normal routine echocardiography without contrast for the exclusion of hypertrophic cardiomyopathy (HCM) also had CMR that was diagnostic of apical HCM. RESULTS: Apical HCM detected by CMR could be morphologically severe with wall thickness up to 28 mm, or mild. The extent of repolarisation abnormalities did not correlate to the morphological severity. CONCLUSIONS: In patients with unexplained repolarisation abnormalities, a normal routine echocardiogram without contrast does not exclude apical HCM. Further imaging with CMR or contrast echocardiography may be required. The reliance on routine echocardiography to exclude apical HCM may have led to underreporting of this condition.
OBJECTIVE: To investigate the role of cardiovascular magnetic resonance (CMR) in a series of patients with ECG repolarisation changes and normal echocardiography. PATIENTS AND DESIGN: 10 patients with anterolateral T wave inversion for which there was no obvious pathological cause who had normal routine echocardiography without contrast for the exclusion of hypertrophic cardiomyopathy (HCM) also had CMR that was diagnostic of apical HCM. RESULTS: Apical HCM detected by CMR could be morphologically severe with wall thickness up to 28 mm, or mild. The extent of repolarisation abnormalities did not correlate to the morphological severity. CONCLUSIONS: In patients with unexplained repolarisation abnormalities, a normal routine echocardiogram without contrast does not exclude apical HCM. Further imaging with CMR or contrast echocardiography may be required. The reliance on routine echocardiography to exclude apical HCM may have led to underreporting of this condition.
Authors: Maria J Eriksson; Brian Sonnenberg; Anna Woo; Paul Rakowski; Thomas G Parker; E Douglas Wigle; Harry Rakowski Journal: J Am Coll Cardiol Date: 2002-02-20 Impact factor: 24.094
Authors: H Thiele; E Nagel; I Paetsch; B Schnackenburg; A Bornstedt; M Kouwenhoven; A Wahl; G Schuler; E Fleck Journal: J Magn Reson Imaging Date: 2001-10 Impact factor: 4.813
Authors: J Suzuki; R Shimamoto; J Nishikawa; T Yamazaki; T Tsuji; F Nakamura; W S Shin; T Nakajima; T Toyo-Oka; K Ohotomo Journal: J Am Coll Cardiol Date: 1999-01 Impact factor: 24.094
Authors: R Parker Ward; Lynn Weinert; Kirk T Spencer; Kathy T Furlong; James Bednarz; Jeanne DeCara; Roberto M Lang Journal: J Am Soc Echocardiogr Date: 2002-04 Impact factor: 5.251