PURPOSE: To evaluate urinary function and bother after prostate brachytherapy (PB) in patients who have had prior transurethral resection of the prostate (TURP). METHODS AND MATERIALS: A total of 171 patients with stage T1a-T2b prostate cancer, Gleason score <or=7 who underwent prior TURP received PB at a single institution. In January 2002, all 171 patients were mailed the University of California-Los Angeles Prostate Cancer Index and International Prostate Symptom Score sheet. One hundred patients (60%) returned completed surveys. Time of TURP before implant ranged from 2 to 300 months (median, 6.5 years). Mean patient age was 74 +/- 5.2 years, follow-up time after implant ranged from 6.1 to 50.9 months (median, 25 months). RESULTS: The mean urinary function score and bother score for the entire study group was 83.5 +/- 19.5 and 82.5 +/- 23.7, respectively. Multivariate analysis revealed higher pretreatment International Prostate Symptom Scores to have significant negative impact (p = 0.001) on urinary function and bother scores. CONCLUSION: With accurate ultrasound identification of the urethral defect and precise dosimetry, brachytherapy can be performed in selected patients who have had prior TURP with resultant low impact on urinary function and bother scores.
PURPOSE: To evaluate urinary function and bother after prostate brachytherapy (PB) in patients who have had prior transurethral resection of the prostate (TURP). METHODS AND MATERIALS: A total of 171 patients with stage T1a-T2b prostate cancer, Gleason score <or=7 who underwent prior TURP received PB at a single institution. In January 2002, all 171 patients were mailed the University of California-Los Angeles Prostate Cancer Index and International Prostate Symptom Score sheet. One hundred patients (60%) returned completed surveys. Time of TURP before implant ranged from 2 to 300 months (median, 6.5 years). Mean patient age was 74 +/- 5.2 years, follow-up time after implant ranged from 6.1 to 50.9 months (median, 25 months). RESULTS: The mean urinary function score and bother score for the entire study group was 83.5 +/- 19.5 and 82.5 +/- 23.7, respectively. Multivariate analysis revealed higher pretreatment International Prostate Symptom Scores to have significant negative impact (p = 0.001) on urinary function and bother scores. CONCLUSION: With accurate ultrasound identification of the urethral defect and precise dosimetry, brachytherapy can be performed in selected patients who have had prior TURP with resultant low impact on urinary function and bother scores.
Authors: Bradley J Stish; Brian J Davis; Lance A Mynderse; Robert H McLaren; Christopher L Deufel; Richard Choo Journal: Transl Androl Urol Date: 2018-06
Authors: Pedro J Prada; Javier Anchuelo; Ana Garcia Blanco; Gema Paya; Juan Cardenal; Enrique Acuna; Maria Ferri; Andres Vazquez; Maite Pacheco; Jesica Sanchez Journal: Int Braz J Urol Date: 2016 Jan-Feb Impact factor: 1.541