Literature DB >> 15143210

The sarcoplasmic reticulum, Ca2+ trapping, and wave mechanisms in smooth muscle.

John G McCarron1, Karen N Bradley, Debbi MacMillan, Susan Chalmers, Thomas C Muir.   

Abstract

The sarcoplasmic reticulum (SR) and apposed regions of the sarcolemma passively trap Ca2+ entering the cell to limit the rise in cytoplasmic Ca2+ concentration without SR pump involvement. When "leaky," the SR facilitates Ca2+ entry to the cytoplasm. SR Ca2+ release via inositol 1,4,5-trisphosphate receptors (IP(3)Rs) propagates as calcium waves; IP(3)Rs alone account for wave propagation.

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Year:  2004        PMID: 15143210     DOI: 10.1152/nips.01518.2004

Source DB:  PubMed          Journal:  News Physiol Sci        ISSN: 0886-1714


  8 in total

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Review 2.  Calcium events in smooth muscles and their interstitial cells; physiological roles of sparks.

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Authors:  Rebecca E Haddock; Caryl E Hill
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Review 4.  Regulation of smooth muscle excitation and contraction.

Authors:  K M Sanders
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Journal:  Am J Physiol Cell Physiol       Date:  2010-05-05       Impact factor: 4.249

6.  Type 1 inositol 1,4,5-trisphosphate receptors mediate UTP-induced cation currents, Ca2+ signals, and vasoconstriction in cerebral arteries.

Authors:  Guiling Zhao; Adebowale Adebiyi; Eva Blaskova; Qi Xi; Jonathan H Jaggar
Journal:  Am J Physiol Cell Physiol       Date:  2008-09-17       Impact factor: 4.249

7.  Sub-plasmalemmal [Ca2+]i upstroke in myocytes of the guinea-pig small intestine evoked by muscarinic stimulation: IP3R-mediated Ca2+ release induced by voltage-gated Ca2+ entry.

Authors:  D V Gordienko; M I Harhun; M V Kustov; V Pucovský; T B Bolton
Journal:  Cell Calcium       Date:  2007-06-13       Impact factor: 6.817

Review 8.  Examining the role of mitochondria in Ca²⁺ signaling in native vascular smooth muscle.

Authors:  John G McCarron; Marnie L Olson; Calum Wilson; Mairi E Sandison; Susan Chalmers
Journal:  Microcirculation       Date:  2013-05       Impact factor: 2.628

  8 in total

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