Literature DB >> 15139748

Vanilloid receptor TRPV1 antagonists as the next generation of painkillers. Are we putting the cart before the horse?

Arpad Szallasi1, Giovanni Appendino.   

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Year:  2004        PMID： 15139748     DOI： 10.1021/jm030560j

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  20 in total

1.  TRPV1 channels mediate long-term depression at synapses on hippocampal interneurons.

Authors:  Helen E Gibson; Jeffrey G Edwards; Rachel S Page; Matthew J Van Hook; Julie A Kauer
Journal:  Neuron       Date:  2008-03-13       Impact factor: 17.173

2.  Physiology and pharmacology of the vanilloid receptor.

Authors:  Angel Messeguer; Rosa Planells-Cases; Antonio Ferrer-Montiel
Journal:  Curr Neuropharmacol       Date:  2006-01       Impact factor: 7.363

3.  Analgesic actions of N-arachidonoyl-serotonin, a fatty acid amide hydrolase inhibitor with antagonistic activity at vanilloid TRPV1 receptors.

Authors:  S Maione; L De Petrocellis; V de Novellis; A Schiano Moriello; S Petrosino; E Palazzo; F Sca Rossi; D F Woodward; V Di Marzo
Journal:  Br J Pharmacol       Date:  2007-02-05       Impact factor: 8.739

4.  Structure-activity relationships of 1,4-dihydropyridines that act as enhancers of the vanilloid receptor 1 (TRPV1).

Authors:  Eun Joo Roh; Jason M Keller; Zoltan Olah; Michael J Iadarola; Kenneth A Jacobson
Journal:  Bioorg Med Chem       Date:  2008-08-26       Impact factor: 3.641

Review 5.  Small molecule vanilloid TRPV1 receptor antagonists approaching drug status: can they live up to the expectations?

Authors:  Arpad Szallasi
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2006-06-14       Impact factor: 3.000

Review 6.  Metabolism of capsaicinoids by P450 enzymes: a review of recent findings on reaction mechanisms, bio-activation, and detoxification processes.

Authors:  Christopher A Reilly; Garold S Yost
Journal:  Drug Metab Rev       Date:  2006       Impact factor: 4.518

7.  Effects of High-Dose Capsaicin on TMD Subjects: A Randomized Clinical Study.

Authors:  B K Campbell; R B Fillingim; S Lee; R Brao; D D Price; J K Neubert
Journal:  JDR Clin Trans Res       Date:  2016-10-26

Review 8.  TRP channels: potential drug target for neuropathic pain.

Authors:  Lovish Marwaha; Yashika Bansal; Raghunath Singh; Priyanka Saroj; Ranjana Bhandari; Anurag Kuhad
Journal:  Inflammopharmacology       Date:  2016-10-18       Impact factor: 4.473

Review 9.  Use of sensory methods for detecting target engagement in clinical trials of new analgesics.

Authors:  Boris A Chizh; Christine N Sang
Journal:  Neurotherapeutics       Date:  2009-10       Impact factor: 7.620

Review 10.  TRP channels and analgesia.

Authors:  Louis S Premkumar; Mruvil Abooj
Journal:  Life Sci       Date:  2012-08-14       Impact factor: 5.037
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