Literature DB >> 15139563

The ideal inhaler: design and characteristics to improve outcomes.

Brian J O'Connor1.   

Abstract

Inhalation therapy is Likely to continue to dominate asthma treatment. The pressurised metered dose inhaler (pMDI) accounts for most of the inhaler market world-wide, but is inefficient and difficult to use. Dry powder inhalers (DPIs) have several advantages over MDIs. They are breath-activated, easy and convenient to use and environmentally friendly. The Turbuhaler is the most widely used DPI, offering good deposition with sufficient inspiratory flow, but it provides no confirmation of dosing, exhibits high dose variation, has a high intrinsic resistance, and inspiratory flow profile-dependent drug deposition. The Novolizer (VIATRIS, Frankfurt, Germany) is a new DPI which has several characteristics of an 'ideal' inhaler. It is convenient and easy to use, demonstrate and teach, provides accurate and consistent drug delivery and provides patients with feedback of dose taken. The Novolizer is a promising new delivery system for inhalation therapy.

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Year:  2004        PMID: 15139563     DOI: 10.1016/j.rmed.2004.02.006

Source DB:  PubMed          Journal:  Respir Med        ISSN: 0954-6111            Impact factor:   3.415


  8 in total

Review 1.  Devices for dry powder drug delivery to the lung.

Authors:  Kai Berkenfeld; Alf Lamprecht; Jason T McConville
Journal:  AAPS PharmSciTech       Date:  2015-05-12       Impact factor: 3.246

2.  Investigation into alternative sugars as potential carriers for dry powder formulation of budesonide.

Authors:  Mohammed-Nurul Momin; Atoosa Hedayati; Ali Nokhodchi
Journal:  Bioimpacts       Date:  2011-08-05

3.  Medication Tracking: Design and Fabrication of a Dry Powder Inhaler with Integrated Acoustic Element by 3D Printing.

Authors:  Yongquan Li; Adam Bohr; Henrik Jensen; Jukka Rantanen; Claus Cornett; Moritz Beck-Broichsitter; Johan Peter Bøtker
Journal:  Pharm Res       Date:  2020-01-21       Impact factor: 4.200

4.  Dry powder inhalers and the right things to remember: a concept review.

Authors:  Roberto W Dal Negro
Journal:  Multidiscip Respir Med       Date:  2015-04-03

5.  Cultural and linguistic validation of the NHQ-2 Questionnaire: a specific instrument for assessing patient's usability of inhalation devices.

Authors:  Roberto W Dal Negro; Massimiliano Povero
Journal:  Multidiscip Respir Med       Date:  2016-08-23

Review 6.  Matching Inhaler Devices with Patients: The Role of the Primary Care Physician.

Authors:  Alan Kaplan; David Price
Journal:  Can Respir J       Date:  2018-05-23       Impact factor: 2.409

Review 7.  Narrative Review of the Role of Patient-Reported Outcomes and Inhaler Handling Errors in the Control of Asthma and COPD.

Authors:  Raúl De Simón Gutiérrez; Raúl Piedra Castro
Journal:  Curr Allergy Asthma Rep       Date:  2022-09-10       Impact factor: 4.919

8.  Assessment of inhalation errors, training time and patient preference for DuoResp® Spiromax® and Symbicort® Turbuhaler® in patients with asthma and COPD.

Authors:  Jordi Giner; Marta Villarnovo Cerrillo; Jaime Aboín Sierra; Laura Casas Herrero; Oliver Patino; Vicente Plaza
Journal:  Eur Clin Respir J       Date:  2020-10-18
  8 in total

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