Literature DB >> 15138193

Toll-like receptor 2 Arg677Trp polymorphism is associated with susceptibility to tuberculosis in Tunisian patients.

Meriem Ben-Ali1, Mohamed-Ridha Barbouche, Soufia Bousnina, Abdellatif Chabbou, Koussay Dellagi.   

Abstract

Toll-like receptor 2 (TLR2) is critical in the immune response to mycobacteria. Herein, we report that the frequency of a human TLR2 Arg677Trp polymorphism (C2029T nucleotide substitution) in tuberculosis patients in Tunisia is significantly higher than in healthy controls (P < 0.0001). This finding suggests that this polymorphism could be a risk factor for tuberculosis.

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Year:  2004        PMID： 15138193      PMCID： PMC404573          DOI： 10.1128/CDLI.11.3.625-626.2004

Source DB:  PubMed          Journal:  Clin Diagn Lab Immunol        ISSN： 1071-412X


  13 in total

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Journal:  Nature       Date:  1999-10-21       Impact factor: 49.962

2.  TLR4 mutations are associated with endotoxin hyporesponsiveness in humans.

Authors:  N C Arbour; E Lorenz; B C Schutte; J Zabner; J N Kline; M Jones; K Frees; J L Watt; D A Schwartz
Journal:  Nat Genet       Date:  2000-06       Impact factor: 38.330

3.  MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways.

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Journal:  Mol Cell       Date:  1998-08       Impact factor: 17.970

4.  Detection of Toll-like receptor 2 (TLR2) mutation in the lepromatous leprosy patients.

Authors:  T J Kang; G T Chae
Journal:  FEMS Immunol Med Microbiol       Date:  2001-07

5.  A human homologue of the Drosophila Toll protein signals activation of adaptive immunity.

Authors:  R Medzhitov; P Preston-Hurlburt; C A Janeway
Journal:  Nature       Date:  1997-07-24       Impact factor: 49.962

6.  Regulation of toll-like receptor 2 expression by macrophages following Mycobacterium avium infection.

Authors:  T Wang; W P Lafuse; B S Zwilling
Journal:  J Immunol       Date:  2000-12-01       Impact factor: 5.422

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Authors:  E Lorenz; J P Mira; K L Cornish; N C Arbour; D A Schwartz
Journal:  Infect Immun       Date:  2000-11       Impact factor: 3.441

8.  Cutting edge: a Toll-like receptor 2 polymorphism that is associated with lepromatous leprosy is unable to mediate mycobacterial signaling.

Authors:  Pierre-Yves Bochud; Thomas R Hawn; Alan Aderem
Journal:  J Immunol       Date:  2003-04-01       Impact factor: 5.422

9.  A polymorphism in the toll-like receptor 2 is associated with IL-12 production from monocyte in lepromatous leprosy.

Authors:  Tae Jin Kang; Seong Beom Lee; Gue Tae Chae
Journal:  Cytokine       Date:  2002-10-21       Impact factor: 3.861

10.  High frequency of polymorphism Arg753Gln of the Toll-like receptor-2 gene detected by a novel allele-specific PCR.

Authors:  Nicolas W J Schröder; Corinna Hermann; Lutz Hamann; Ulf B Göbel; Thomas Hartung; Ralf R Schumann
Journal:  J Mol Med (Berl)       Date:  2003-05-13       Impact factor: 4.599
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  69 in total

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Authors:  M Ioana; B Ferwerda; T S Plantinga; M Stappers; M Oosting; M McCall; A Cimpoeru; F Burada; N Panduru; R Sauerwein; O Doumbo; J W M van der Meer; R van Crevel; L A B Joosten; M G Netea
Journal:  Infect Immun       Date:  2012-02-21       Impact factor: 3.441

2.  Toll-like receptor polymorphisms and tuberculosis susceptibility: A comprehensive meta-analysis.

Authors:  Qin Sun; Qing Zhang; He-Ping Xiao; Chong Bai
Journal:  J Huazhong Univ Sci Technolog Med Sci       Date:  2015-04-16

3.  A new Toll-road from environment to genes for rheumatic fever?

Authors:  Ralf R Schumann; Rolf Keitzer
Journal:  J Mol Med (Berl)       Date:  2005-06-24       Impact factor: 4.599

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Authors:  Frank P Mockenhaupt; Jakob P Cramer; Lutz Hamann; Miriam S Stegemann; Jana Eckert; Na-Ri Oh; Rowland N Otchwemah; Ekkehart Dietz; Stephan Ehrhardt; Nicolas W J Schröder; Ulrich Bienzle; Ralf R Schumann
Journal:  Proc Natl Acad Sci U S A       Date:  2005-12-21       Impact factor: 11.205

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Journal:  Clin Vaccine Immunol       Date:  2007-10-03

Review 6.  Pathogen recognition and inflammatory signaling in innate immune defenses.

Authors:  Trine H Mogensen
Journal:  Clin Microbiol Rev       Date:  2009-04       Impact factor: 26.132

Review 7.  Toll-like receptor signaling in primary immune deficiencies.

Authors:  Paul J Maglione; Noa Simchoni; Charlotte Cunningham-Rundles
Journal:  Ann N Y Acad Sci       Date:  2015-04-30       Impact factor: 5.691

8.  Essential engagement of Toll-like receptor 2 in initiation of early protective Th1 response against rough variants of Mycobacterium abscessus.

Authors:  Jong-Seok Kim; Min-Jung Kang; Woo Sik Kim; Seung Jung Han; Hong Min Kim; Ho Won Kim; Kee Woong Kwon; So Jeong Kim; Seung Bin Cha; Seok-Yong Eum; Won-Jung Koh; Sang-Nae Cho; Jong-Hwan Park; Sung Jae Shin
Journal:  Infect Immun       Date:  2015-02-02       Impact factor: 3.441

9.  Association of VDR gene polymorphisms and 22 bp deletions in the promoter region of TLR2Δ22 (-196-174) with increased risk of pulmonary tuberculosis: A case-control study in tea garden communities of Assam.

Authors:  Kangjam Rekha Devi; Kaustab Mukherjee; Pradipta Kumar Chelleng; Simanta Kalita; Upasana Das; Kanwar Narain
Journal:  J Clin Lab Anal       Date:  2018-05-04       Impact factor: 2.352

10.  Toll-like receptors TLR4 (Asp299Gly and Thr399Ile) and TLR2 (Arg677Trp and Arg753Gln) gene polymorphisms in end-stage renal disease patients on peritoneal dialysis.

Authors:  Kamini Singh; Kashi Nath Prasad; Priyanka Mishra; Jahanarah Khatoon; Narayan Prasad; Amit Gupta; Janmejai Kumar Srivastava
Journal:  Int Urol Nephrol       Date:  2015-10-22       Impact factor: 2.370
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