Literature DB >> 15136859

Unprecedented copper-catalyzed asymmetric conjugate addition of organometallic reagents to alpha,beta-unsaturated lactams.

Mauro Pineschi1, Federica Del Moro, Francesca Gini, Adriaan J Minnaard, Ben L Feringa.   

Abstract

For the first time, an excellent enantioselectivity has been obtained in the conjugate addition of hard organometallic reagents to alpha,beta-unsaturated lactams bearing appropriate protecting-activating groups on the nitrogen.

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Year:  2004        PMID: 15136859     DOI: 10.1039/b403793f

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  3 in total

1.  Catalytic Allylic Oxidation of Cyclic Enamides and 3,4-Dihydro-2H-Pyrans by TBHP.

Authors:  Yang Yu; Ranad Humeidi; James R Alleyn; Michael P Doyle
Journal:  J Org Chem       Date:  2017-08-04       Impact factor: 4.354

Review 2.  Diastereoselective and enantioselective conjugate addition reactions utilizing α,β-unsaturated amides and lactams.

Authors:  Katherine M Byrd
Journal:  Beilstein J Org Chem       Date:  2015-04-23       Impact factor: 2.883

3.  Lewis Acid Enabled Copper-Catalyzed Asymmetric Synthesis of Chiral β-Substituted Amides.

Authors:  Mamen Rodríguez-Fernández; Xingchen Yan; Juan F Collados; Paul B White; Syuzanna R Harutyunyan
Journal:  J Am Chem Soc       Date:  2017-09-29       Impact factor: 15.419

  3 in total

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