Literature DB >> 15136845

Efficient synthesis of a nucleoside-diphospho-exo-glycal displaying time-dependent inactivation of UDP-galactopyranose mutase.

Audrey Caravano1, Stéphane P Vincent, Pierre Sinaÿ.   

Abstract

A short and efficient synthesis of UDP-exo-galactofuranosyl-glycal is presented. This molecule displayed an interesting time-dependent inactivation of UDP-galactopyranose mutase, an essential enzyme of the mycobacterial cell wall biosynthesis.

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Year:  2004        PMID: 15136845     DOI: 10.1039/b402469a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  2 in total

1.  Nucleophilic participation of reduced flavin coenzyme in mechanism of UDP-galactopyranose mutase.

Authors:  He G Sun; Mark W Ruszczycky; Wei-Chen Chang; Christopher J Thibodeaux; Hung-Wen Liu
Journal:  J Biol Chem       Date:  2011-12-20       Impact factor: 5.157

2.  Potent ligands for prokaryotic UDP-galactopyranose mutase that exploit an enzyme subsite.

Authors:  Emily C Dykhuizen; Laura L Kiessling
Journal:  Org Lett       Date:  2009-01-01       Impact factor: 6.005

  2 in total

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