Literature DB >> 15135718

Effectiveness of sotalol treatment in symptomatic Brugada syndrome.

Kathryn A Glatter1, Qing Wang, Mark Keating, Shenghan Chen, Nipavan Chiamvimonvat, Melvin M Scheinman.   

Abstract

We describe a 53-year-old man with recurrent syncopal events and a malignant family history who was treated for 13 years with sotalol drug therapy with no further occurrence of Brugada syndrome symptoms. Genetic testing revealed that he carried a Brugada syndrome sodium channel SCN5A mutation (4189delT). This finding suggests that sotalol may be of therapeutic benefit in such patients.

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Year:  2004        PMID: 15135718     DOI: 10.1016/j.amjcard.2004.02.023

Source DB:  PubMed          Journal:  Am J Cardiol        ISSN: 0002-9149            Impact factor:   2.778


  4 in total

Review 1.  Inherited disorders of voltage-gated sodium channels.

Authors:  Alfred L George
Journal:  J Clin Invest       Date:  2005-08       Impact factor: 14.808

2.  Risk stratification in Brugada syndrome.

Authors:  Kathryn A Glatter; Nipavan Chiamvimonvat; Matti Viitasalo; Qing Wang; Dipika Tuteja
Journal:  Lancet       Date:  2005 Aug 13-19       Impact factor: 79.321

3.  Patient-Specific and Genome-Edited Induced Pluripotent Stem Cell-Derived Cardiomyocytes Elucidate Single-Cell Phenotype of Brugada Syndrome.

Authors:  Ping Liang; Karim Sallam; Haodi Wu; Yingxin Li; Ilanit Itzhaki; Priyanka Garg; Ying Zhang; Vittavat Vermglinchan; Feng Lan; Mingxia Gu; Tingyu Gong; Yan Zhuge; Chunjiang He; Antje D Ebert; Veronica Sanchez-Freire; Jared Churko; Shijun Hu; Arun Sharma; Chi Keung Lam; Melvin M Scheinman; Donald M Bers; Joseph C Wu
Journal:  J Am Coll Cardiol       Date:  2016-11-08       Impact factor: 24.094

Review 4.  Drugs and Brugada syndrome patients: review of the literature, recommendations, and an up-to-date website (www.brugadadrugs.org).

Authors:  Pieter G Postema; Christian Wolpert; Ahmad S Amin; Vincent Probst; Martin Borggrefe; Dan M Roden; Silvia G Priori; Hanno L Tan; Masayasu Hiraoka; Josep Brugada; Arthur A M Wilde
Journal:  Heart Rhythm       Date:  2009-07-08       Impact factor: 6.343

  4 in total

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