| Literature DB >> 15135314 |
Vaclav Vetvicka1, Jean-Claude Yvin.
Abstract
Glucans have a long history as nonspecific biological modulators. A novel glucan-Phycarine-was isolated from sporophytes of Laminaria digitata. Phycarine showed significant stimulation of phagocytic activity as well as potentiation of synthesis and release of IL-1, IL-6 and TNF-alpha. In addition, Phycarine increased NK cell-mediated killing of tumor cells both in vitro and in vivo while acting via complement receptor type 3 (CR3) receptors. Copyright 2004 Elsevier B.V.Entities:
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Year: 2004 PMID: 15135314 DOI: 10.1016/j.intimp.2004.02.007
Source DB: PubMed Journal: Int Immunopharmacol ISSN: 1567-5769 Impact factor: 4.932