Literature DB >> 15134285

Rimonabant Sanofi-Synthélabo.

Jose R Fernandez1, David B Allison.   

Abstract

Rimonabant, an antagonist of central cannabinoid type 1 (CB1) receptors, is being developed by Sanofi-Synthélabo for the potential treatment of obesity and as a potential smoking cessation agent. Phase III trials were initiated for obesity in August 2001 and were ongoing in September 2003. By September 2002, the compound had entered phase III trials for smoking cessation, and these trials were ongoing in September 2003.

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Year:  2004        PMID: 15134285

Source DB:  PubMed          Journal:  Curr Opin Investig Drugs        ISSN: 1472-4472


  25 in total

Review 1.  The endocannabinoid system: role in energy regulation.

Authors:  Thomas F Gamage; Aron H Lichtman
Journal:  Pediatr Blood Cancer       Date:  2012-01       Impact factor: 3.167

Review 2.  Cannabinoid CB1 receptor-interacting proteins: novel targets for central nervous system drug discovery?

Authors:  Tricia H Smith; Laura J Sim-Selley; Dana E Selley
Journal:  Br J Pharmacol       Date:  2010-06       Impact factor: 8.739

3.  Pharmacological characterization of endocannabinoid transport and fatty acid amide hydrolase inhibitors.

Authors:  Amy K Dickason-Chesterfield; Stephanie R Kidd; Steven A Moore; John M Schaus; Bin Liu; George G Nomikos; Christian C Felder
Journal:  Cell Mol Neurobiol       Date:  2006-05-31       Impact factor: 5.046

4.  Rimonabant abolishes sensitivity to workload changes in a progressive ratio procedure.

Authors:  Julie A Marusich; Jenny L Wiley
Journal:  Pharmacol Biochem Behav       Date:  2012-03-09       Impact factor: 3.533

Review 5.  Development of novel pharmacotherapeutics for tobacco dependence: progress and future directions.

Authors:  Dympna Harmey; Patrick R Griffin; Paul J Kenny
Journal:  Nicotine Tob Res       Date:  2012-09-27       Impact factor: 4.244

Review 6.  Recent advances in understanding nicotinic receptor signaling mechanisms that regulate drug self-administration behavior.

Authors:  Luis M Tuesta; Christie D Fowler; Paul J Kenny
Journal:  Biochem Pharmacol       Date:  2011-06-29       Impact factor: 5.858

7.  Search for an endogenous cannabinoid-mediated effect in the sympathetic nervous system.

Authors:  Torsten Pfitzer; Nathalie Niederhoffer; Bela Szabo
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2005-01-20       Impact factor: 3.000

8.  Pharmacogenetic trial of a cannabinoid agonist shows reduced fasting colonic motility in patients with nonconstipated irritable bowel syndrome.

Authors:  Banny S Wong; Michael Camilleri; Irene Busciglio; Paula Carlson; Lawrence A Szarka; Duane Burton; Alan R Zinsmeister
Journal:  Gastroenterology       Date:  2011-07-29       Impact factor: 22.682

9.  Cannabinoid receptor 1 (CNR1) gene variant moderates neural index of cognitive disruption during nicotine withdrawal.

Authors:  D E Evans; S K Sutton; K G Jentink; H-Y Lin; J Y Park; D J Drobes
Journal:  Genes Brain Behav       Date:  2016-09       Impact factor: 3.449

Review 10.  Inhibition of FAAH and activation of PPAR: new approaches to the treatment of cognitive dysfunction and drug addiction.

Authors:  Leigh V Panlilio; Zuzana Justinova; Steven R Goldberg
Journal:  Pharmacol Ther       Date:  2013-01-16       Impact factor: 12.310

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