Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Speckle interferometry applied to pharmacodynamic studies: evaluation of parasite motility.

Literature DB >> 15133648

Speckle interferometry applied to pharmacodynamic studies: evaluation of parasite motility.

J A Pomarico¹, H O Di Rocco, L Alvarez, C Lanusse, L Mottier, C Saumell, R Arizaga, H Rabal, M Trivi.

Abstract

The work reported here describes the application of the optical technique known as dynamic speckle interferometry to evaluate the motility of nematode parasites exposed to different anthelmintic drugs. This technique, a well proven tool for assessing the time evolution of different phenomena, is here successfully used to quantify parasite motility in pharmacodynamic assays. The characterization of the pharmacological properties of anthelmintic drugs is critical to optimize their use in parasite control. Besides, the evaluation of nematode motility is a relevant indicator of the pharmacodynamic effect of anthelmintic drugs. The application of this approach to study the motility of Haemonchus contortus (used as a model of nematode parasites) larvae exposed to different drugs is presented, showing its usefulness.

Entities: Disease Species

Mesh：

Substances：
Anthelmintics

Year: 2004 PMID： 15133648 DOI： 10.1007/s00249-004-0413-4

Source DB: PubMed Journal: Eur Biophys J ISSN： 0175-7571 Impact factor: 1.733

6 in total

1. Mechanistic approaches to quantitate anthelmintic absorption by gastrointestinal nematodes.

Authors: D P Thompson; N F Ho; S M Sims; T G Geary
Journal: Parasitol Today Date: 1993-01

2. Fast algorithm for texture discrimination by use of a separable orthonormal decomposition of the co-occurrence matrix.

Authors: S Allam; M Adel; P Réfrégier
Journal: Appl Opt Date: 1997-11-10 Impact factor: 1.980

3. Tetramisole (dl 2,3,5,6-tetrahydro-6-phenyl-imidazo (2,1-b) thiazole hydrochloride--Nilverm) in the treatment of gastro-intestinal worms and lungworms in domestic animals. 1. Sheep and goats.

Authors: J K Walley
Journal: Vet Rec Date: 1966-03-19 Impact factor: 2.695

Review 4. The absorption, distribution and elimination of anthelmintic drugs: the role of pharmacokinetics.

Authors: J D Baggot; Q A McKellar
Journal: J Vet Pharmacol Ther Date: 1994-12 Impact factor: 1.786

Review 5. Modes of action of anthelmintic drugs.

Authors: R J Martin
Journal: Vet J Date: 1997-07 Impact factor: 2.688

6. A new in vitro assay of benzimidazole activity against adult Oesophagostomum dentatum.

Authors: M B Petersen; C Friis; H Bjørn
Journal: Int J Parasitol Date: 1997-11 Impact factor: 3.981

6 in total

7 in total

1. Live biospeckle laser imaging of root tissues.

Authors: Roberto A Braga; L Dupuy; M Pasqual; R R Cardoso
Journal: Eur Biophys J Date: 2009-03-06 Impact factor: 1.733

2. Continuous, high-resolution biospeckle imaging reveals a discrete zone of activity at the root apex that responds to contact with obstacles.

Authors: K M Ribeiro; B Barreto; M Pasqual; P J White; R A Braga; L X Dupuy
Journal: Ann Bot Date: 2013-11-26 Impact factor: 4.357

Speckle interferometry applied to pharmacodynamic studies: evaluation of parasite motility.

1. Mechanistic approaches to quantitate anthelmintic absorption by gastrointestinal nematodes.

2. Fast algorithm for texture discrimination by use of a separable orthonormal decomposition of the co-occurrence matrix.

3. Tetramisole (dl 2,3,5,6-tetrahydro-6-phenyl-imidazo (2,1-b) thiazole hydrochloride--Nilverm) in the treatment of gastro-intestinal worms and lungworms in domestic animals. 1. Sheep and goats.

Review 4. The absorption, distribution and elimination of anthelmintic drugs: the role of pharmacokinetics.

Review 5. Modes of action of anthelmintic drugs.

6. A new in vitro assay of benzimidazole activity against adult Oesophagostomum dentatum.

1. Live biospeckle laser imaging of root tissues.

2. Continuous, high-resolution biospeckle imaging reveals a discrete zone of activity at the root apex that responds to contact with obstacles.

3. Non-invasive in situ monitoring of bone scaffold activity by speckle pattern analysis.

4. Relation of biospeckle activity with quality attributes of apples.

5. Determination of maize hardness by biospeckle and fuzzy granularity.

6. New live screening of plant-nematode interactions in the rhizosphere.

7. Dynamic biospeckle analysis, a new tool for the fast screening of plant nematicide selectivity.