AIMS: To determine the concentration of vitamin E in normal maternal and umbilical cord blood pairs, and to study the relationship between vitamin E content in maternal lipoprotein fractions and umbilical cord blood. METHODS: Fifty healthy pregnant women were recruited randomly at term and blood samples were drawn from the mothers at delivery and cord blood was obtained immediately postpartum. Vitamin E was determined by HPLC in plasma, in the different lipoprotein fractions and in the placenta. Plasma levels of triglycerides and cholesterol were also measured. RESULTS: The concentration of vitamin E in umbilical cord plasma was 250 microg/dl, lower than in maternal plasma (1,460 microg/dl) (p < 0.001). A positive correlation was found between the vitamin E concentration in maternal plasma, LDL and VLDL and in the umbilical cord plasma. In contrast, no correlation was found between maternal HDL concentration and umbilical cord blood. CONCLUSION: These results show that the concentration of vitamin E in umbilical cord blood is lower than in maternal plasma. LDL and VLDL seem to be the main source of vitamin E for the fetus. Copyright 2004 S. Karger AG, Basel
AIMS: To determine the concentration of vitamin E in normal maternal and umbilical cord blood pairs, and to study the relationship between vitamin E content in maternal lipoprotein fractions and umbilical cord blood. METHODS: Fifty healthy pregnant women were recruited randomly at term and blood samples were drawn from the mothers at delivery and cord blood was obtained immediately postpartum. Vitamin E was determined by HPLC in plasma, in the different lipoprotein fractions and in the placenta. Plasma levels of triglycerides and cholesterol were also measured. RESULTS: The concentration of vitamin E in umbilical cord plasma was 250 microg/dl, lower than in maternal plasma (1,460 microg/dl) (p < 0.001). A positive correlation was found between the vitamin E concentration in maternal plasma, LDL and VLDL and in the umbilical cord plasma. In contrast, no correlation was found between maternal HDL concentration and umbilical cord blood. CONCLUSION: These results show that the concentration of vitamin E in umbilical cord blood is lower than in maternal plasma. LDL and VLDL seem to be the main source of vitamin E for the fetus. Copyright 2004 S. Karger AG, Basel
Authors: Svetlana Didenco; Melanie B Gillingham; Mitzi D Go; Scott W Leonard; Maret G Traber; Cindy T McEvoy Journal: Am J Clin Nutr Date: 2010-12-15 Impact factor: 7.045
Authors: Martin Alcala; Victoria E Bolado; Isabel Sánchez-Vera; Sonia Clapés; Francisco Dasí; Guillermo Sáez; Esther Carrera; Fabiola Alvarez-Gallego; Mary R Loeken; Marta Viana Journal: Antioxidants (Basel) Date: 2021-07-23