OBJECTIVE: To evaluate the collagen changes of allografting an acellular dermal matrix (allo-ADM). METHODS: The allo-ADM was grafted underneath the skin of SD rats. The content of collagen and the proportion of type I to III collagen was examined with a biochemical assay. RESULT: The content of collagen and the proportion of type I to III collagen in the allo-ADM group showed no significant changes. CONCLUSION: The allo-ADM could keep long time in the body and it may be an ideal material for soft tissue filling.
OBJECTIVE: To evaluate the collagen changes of allografting an acellular dermal matrix (allo-ADM). METHODS: The allo-ADM was grafted underneath the skin of SD rats. The content of collagen and the proportion of type I to III collagen was examined with a biochemical assay. RESULT: The content of collagen and the proportion of type I to III collagen in the allo-ADM group showed no significant changes. CONCLUSION: The allo-ADM could keep long time in the body and it may be an ideal material for soft tissue filling.