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Literature DB >> 15131650

Chemogenomics: an emerging strategy for rapid target and drug discovery.

Markus Bredel¹, Edgar Jacoby.

Abstract

Mesh：

Year: 2004 PMID： 15131650 DOI： 10.1038/nrg1317

Source DB: PubMed Journal: Nat Rev Genet ISSN： 1471-0056 Impact factor: 53.242

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64 in total

1. Mining relational paths in integrated biomedical data.

Authors: Bing He; Jie Tang; Ying Ding; Huijun Wang; Yuyin Sun; Jae Hong Shin; Bin Chen; Ganesh Moorthy; Judy Qiu; Pankaj Desai; David J Wild
Journal: PLoS One Date: 2011-12-06 Impact factor: 3.240

Review 2. Virtual screening: an endless staircase?

Authors: Gisbert Schneider
Journal: Nat Rev Drug Discov Date: 2010-04 Impact factor: 84.694

3. Supporting retrieval of diverse biomedical data using evidence-aware queries.

Authors: Eithon Cadag; Peter Tarczy-Hornoch
Journal: J Biomed Inform Date: 2010-07-17 Impact factor: 6.317

Review 4. Patient-Derived Xenografts as a Model System for Radiation Research.

Authors: Christopher D Willey; Ashley N Gilbert; Joshua C Anderson; George Yancey Gillespie
Journal: Semin Radiat Oncol Date: 2015-05-14 Impact factor: 5.934

5. Quantifying the relationships among drug classes.

Authors: Jérôme Hert; Michael J Keiser; John J Irwin; Tudor I Oprea; Brian K Shoichet
Journal: J Chem Inf Model Date: 2008-03-13 Impact factor: 4.956

6. Exploring structure-selectivity relationships of biogenic amine GPCR antagonists using similarity searching and dynamic compound mapping.

Authors: Ingo Vogt; Hany E A Ahmed; Jens Auer; Jürgen Bajorath
Journal: Mol Divers Date: 2008-03-04 Impact factor: 2.943

Chemogenomics: an emerging strategy for rapid target and drug discovery.

1. Mining relational paths in integrated biomedical data.

Review 2. Virtual screening: an endless staircase?

3. Supporting retrieval of diverse biomedical data using evidence-aware queries.

Review 4. Patient-Derived Xenografts as a Model System for Radiation Research.

5. Quantifying the relationships among drug classes.

6. Exploring structure-selectivity relationships of biogenic amine GPCR antagonists using similarity searching and dynamic compound mapping.

Review 7. Chemical probes and drug leads from advances in synthetic planning and methodology.

8. Creation and manipulation of common functional groups en route to a skeletally diverse chemical library.

Review 9. Applications of chemogenomic library screening in drug discovery.

Review 10. Machine learning for in silico virtual screening and chemical genomics: new strategies.