Literature DB >> 15131193

Comparison of chlorhexidine and tincture of iodine for skin antisepsis in preparation for blood sample collection.

Joan Barenfanger1, Cheryl Drake, Jerry Lawhorn, Steven J Verhulst.   

Abstract

Rates of contamination of blood cultures obtained when skin was prepared with iodine tincture versus chlorhexidine were compared. For iodine tincture, the contamination rate was 2.7%; for chlorhexidine, it was 3.1%. The 0.41% difference is not statistically significant. Chlorhexidine has comparable effectiveness and is safer, cheaper, and preferred by staff, so it is an alternative to iodine tincture.

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Year:  2004        PMID： 15131193      PMCID： PMC404630          DOI： 10.1128/JCM.42.5.2216-2217.2004

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  9 in total

Review 1.  Neonatal skin care.

Authors:  G L Darmstadt; J G Dinulos
Journal:  Pediatr Clin North Am       Date:  2000-08       Impact factor: 3.278

2.  Chlorhexidine compared with povidone-iodine as skin preparation before blood culture. A randomized, controlled trial.

Authors:  O Mimoz; A Karim; A Mercat; M Cosseron; B Falissard; F Parker; C Richard; K Samii; P Nordmann
Journal:  Ann Intern Med       Date:  1999-12-07       Impact factor: 25.391

3.  Prospective randomised trial of povidone-iodine, alcohol, and chlorhexidine for prevention of infection associated with central venous and arterial catheters.

Authors:  D G Maki; M Ringer; C J Alvarado
Journal:  Lancet       Date:  1991-08-10       Impact factor: 79.321

4.  Comparison of 10% povidone-iodine and 0.5% chlorhexidine gluconate for the prevention of peripheral intravenous catheter colonization in neonates: a prospective trial.

Authors:  J S Garland; R K Buck; P Maloney; D M Durkin; S Toth-Lloyd; M Duffy; P Szocik; T L McAuliffe; D Goldmann
Journal:  Pediatr Infect Dis J       Date:  1995-06       Impact factor: 2.129

5.  A randomized trial comparing povidone-iodine to a chlorhexidine gluconate-impregnated dressing for prevention of central venous catheter infections in neonates.

Authors:  J S Garland; C P Alex; C D Mueller; D Otten; C Shivpuri; M C Harris; M Naples; J Pellegrini; R K Buck; T L McAuliffe; D A Goldmann; D G Maki
Journal:  Pediatrics       Date:  2001-06       Impact factor: 7.124

Review 6.  Topical therapies and medications in the pediatric patient.

Authors:  D W Metry; A A Hebert
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7.  Prospective, randomized trial of two antiseptic solutions for prevention of central venous or arterial catheter colonization and infection in intensive care unit patients.

Authors:  O Mimoz; L Pieroni; C Lawrence; A Edouard; Y Costa; K Samii; C Brun-Buisson
Journal:  Crit Care Med       Date:  1996-11       Impact factor: 7.598

8.  Chlorhexidine versus povidone iodine in preventing colonization of continuous epidural catheters in children: a randomized, controlled trial.

Authors:  B Kinirons; O Mimoz; L Lafendi; T Naas; J Meunier; P Nordmann
Journal:  Anesthesiology       Date:  2001-02       Impact factor: 7.892

9.  Skin antisepsis kits containing alcohol and chlorhexidine gluconate or tincture of iodine are associated with low rates of blood culture contamination.

Authors:  Barbara W Trautner; Jill E Clarridge; Rabih O Darouiche
Journal:  Infect Control Hosp Epidemiol       Date:  2002-07       Impact factor: 3.254
  9 in total
  4 in total

Review 1.  Updated review of blood culture contamination.

Authors:  Keri K Hall; Jason A Lyman
Journal:  Clin Microbiol Rev       Date:  2006-10       Impact factor: 26.132

2.  Chlorhexidine versus Tincture of Iodine for Reduction of Blood Culture Contamination Rates: a Prospective Randomized Crossover Study.

Authors:  Elizabeth Story-Roller; Melvin P Weinstein
Journal:  J Clin Microbiol       Date:  2016-10-05       Impact factor: 5.948

Review 3.  Practical Guidance for Clinical Microbiology Laboratories: A Comprehensive Update on the Problem of Blood Culture Contamination and a Discussion of Methods for Addressing the Problem

Authors:  Gary V Doern; Karen C Carroll; Daniel J Diekema; Kevin W Garey; Mark E Rupp; Melvin P Weinstein; Daniel J Sexton
Journal:  Clin Microbiol Rev       Date:  2019-10-30       Impact factor: 26.132

Review 4.  The forgotten role of alcohol: a systematic review and meta-analysis of the clinical efficacy and perceived role of chlorhexidine in skin antisepsis.

Authors:  Matthias Maiwald; Edwin S Y Chan
Journal:  PLoS One       Date:  2012-09-05       Impact factor: 3.240
  4 in total

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