Literature DB >> 15130834

MHCPred: bringing a quantitative dimension to the online prediction of MHC binding.

Pingping Guan1, Irini A Doytchinova, Christianna Zygouri, Darren R Flower.   

Abstract

The accurate prediction of T cell epitopes is one of the key aspirations of immunoinformatics. We have developed a partial least squares-based, robust multivariate statistical method for the quantitative prediction of peptide binding to major histocompatibility complexes (MHCs), the principal checkpoint on the antigen presentation pathway. As a service to the immunobiology community, we have made a Perl implementation of the method available as a World Wide Web server.

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Year:  2003        PMID: 15130834

Source DB:  PubMed          Journal:  Appl Bioinformatics        ISSN: 1175-5636


  23 in total

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9.  Computationally driven deletion of broadly distributed T cell epitopes in a biotherapeutic candidate.

Authors:  Regina S Salvat; Andrew S Parker; Andrew Guilliams; Yoonjoo Choi; Chris Bailey-Kellogg; Karl E Griswold
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10.  Protegen: a web-based protective antigen database and analysis system.

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