Literature DB >> 15130806

Genomic Object Net: I. A platform for modelling and simulating biopathways.

Masao Nagasaki1, Atsushi Doi, Hiroshi Matsuno, Satoru Miyano.   

Abstract

Genomic Object Net (GON) 1.0 is a software package for creating models and simulations of biopathways. Its core architecture employs the notion of a hybrid functional Petri net with extension (HFPNe). HFPNe can seamlessly handle discrete and continuous objects and events while keeping the model components themselves simple. With the feature and graphical model editor, biopathways can be modelled intuitively and simulated on GON. The subsequent output of the simulation results can be evaluated in customised views on GON Visualizer by writing an XML file. Additionally, GON provides a tool to transform biopathway models in KEGG and BioCyc to the GON XML files for modelling and simulation. The tool avoids a lot of tedious work by users, enabling them to focus on the biological model.

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Year:  2003        PMID: 15130806

Source DB:  PubMed          Journal:  Appl Bioinformatics        ISSN: 1175-5636


  17 in total

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Authors:  Bud Mishra
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2.  BFL: a node and edge betweenness based fast layout algorithm for large scale networks.

Authors:  Tatsunori B Hashimoto; Masao Nagasaki; Kaname Kojima; Satoru Miyano
Journal:  BMC Bioinformatics       Date:  2009-01-15       Impact factor: 3.169

3.  An efficient biological pathway layout algorithm combining grid-layout and spring embedder for complicated cellular location information.

Authors:  Kaname Kojima; Masao Nagasaki; Satoru Miyano
Journal:  BMC Bioinformatics       Date:  2010-06-18       Impact factor: 3.169

4.  An efficient grid layout algorithm for biological networks utilizing various biological attributes.

Authors:  Kaname Kojima; Masao Nagasaki; Euna Jeong; Mitsuru Kato; Satoru Miyano
Journal:  BMC Bioinformatics       Date:  2007-03-06       Impact factor: 3.169

5.  Computational modeling with forward and reverse engineering links signaling network and genomic regulatory responses: NF-kappaB signaling-induced gene expression responses in inflammation.

Authors:  Shih Chi Peng; David Shan Hill Wong; Kai Che Tung; Yan Yu Chen; Chun Cheih Chao; Chien Hua Peng; Yung Jen Chuang; Chuan Yi Tang
Journal:  BMC Bioinformatics       Date:  2010-06-08       Impact factor: 3.169

6.  Simulation-based model checking approach to cell fate specification during Caenorhabditis elegans vulval development by hybrid functional Petri net with extension.

Authors:  Chen Li; Masao Nagasaki; Kazuko Ueno; Satoru Miyano
Journal:  BMC Syst Biol       Date:  2009-04-27

7.  Orengedokuto and berberine improve indomethacin-induced small intestinal injury via adenosine.

Authors:  Yoko Watanabe-Fukuda; Masahiro Yamamoto; Naoko Miura; Masato Fukutake; Atsushi Ishige; Rui Yamaguchi; Masao Nagasaki; Ayumu Saito; Seiya Imoto; Satoru Miyano; Junzo Takeda; Kenji Watanabe
Journal:  J Gastroenterol       Date:  2009-03-25       Impact factor: 7.527

8.  Evolution of multiple phosphodiesterase isoforms in stickleback involved in cAMP signal transduction pathway.

Authors:  Yukuto Sato; Yasuyuki Hashiguchi; Mutsumi Nishida
Journal:  BMC Syst Biol       Date:  2009-02-20

9.  Recursive regularization for inferring gene networks from time-course gene expression profiles.

Authors:  Teppei Shimamura; Seiya Imoto; Rui Yamaguchi; André Fujita; Masao Nagasaki; Satoru Miyano
Journal:  BMC Syst Biol       Date:  2009-04-22

10.  LucidDraw: efficiently visualizing complex biochemical networks within MATLAB.

Authors:  Sheng He; Juan Mei; Guiyang Shi; Zhengxiang Wang; Weijiang Li
Journal:  BMC Bioinformatics       Date:  2010-01-15       Impact factor: 3.169

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