Literature DB >> 15130535

Evaluation of antiviral activity against human herpesvirus 8 (HHV-8) and Epstein-Barr virus (EBV) by a quantitative real-time PCR assay.

Claudia Friedrichs1, Johan Neyts, Gabor Gaspar, Erik De Clercq, Peter Wutzler.   

Abstract

A real-time quantitative PCR was developed to assess antiviral activity of molecules against human herpesvirus 8 (HHV-8) and the Epstein-Barr virus (EBV). The antiviral activity of the reference molecules acyclovir, ganciclovir, cidofovir, adefovir and brivudin, as assessed by this methodology, proved very similar to the activity as determined by a DNA-DNA hybridisation method.

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Year:  2004        PMID： 15130535     DOI： 10.1016/j.antiviral.2003.12.005

Source DB:  PubMed          Journal:  Antiviral Res        ISSN： 0166-3542            Impact factor:   5.970


  20 in total

1.  Treatment with valacyclovir, famciclovir, or antiretrovirals reduces human herpesvirus-8 replication in HIV-1 seropositive men.

Authors:  Ashok Cattamanchi; Misty Saracino; Stacy Selke; Meei-Li Huang; Amalia Magaret; Connie Celum; Lawrence Corey; Anna Wald; Corey Casper
Journal:  J Med Virol       Date:  2011-10       Impact factor: 2.327

2.  Evaluation of novel acyclic nucleoside phosphonates against human and animal gammaherpesviruses revealed an altered metabolism of cyclic prodrugs upon Epstein-Barr virus reactivation in P3HR-1 cells.

Authors:  Natacha Coen; Sophie Duraffour; Lieve Naesens; Marcela Krecmerová; Joost Van den Oord; Robert Snoeck; Graciela Andrei
Journal:  J Virol       Date:  2013-09-11       Impact factor: 5.103

3.  A rapid DNA hybridization assay for the evaluation of antiviral compounds against Epstein-Barr virus.

Authors:  Mark N Prichard; Shannon L Daily; Geraldine M Jefferson; Amie L Perry; Earl R Kern
Journal:  J Virol Methods       Date:  2007-05-30       Impact factor: 2.014

4.  Antimicrobial sulfonamides clear latent Kaposi sarcoma herpesvirus infection and impair MDM2-p53 complex formation.

Authors:  Fabrizio Angius; Enrica Piras; Sabrina Uda; Clelia Madeddu; Roberto Serpe; Rachele Bigi; Wuguo Chen; Dirk P Dittmer; Raffaello Pompei; Angela Ingianni
Journal:  J Antibiot (Tokyo)       Date:  2017-06-14       Impact factor: 2.649

5.  Spectrum of activity and mechanisms of resistance of various nucleoside derivatives against gammaherpesviruses.

Authors:  Natacha Coen; Sophie Duraffour; Dimitri Topalis; Robert Snoeck; Graciela Andrei
Journal:  Antimicrob Agents Chemother       Date:  2014-09-29       Impact factor: 5.191

Review 6.  Current and potential treatments for ubiquitous but neglected herpesvirus infections.

Authors:  Jonathan E Gable; Timothy M Acker; Charles S Craik
Journal:  Chem Rev       Date:  2014-10-02       Impact factor: 60.622

Review 7.  Castleman's disease: from basic mechanisms to molecular therapeutics.

Authors:  Hazem E El-Osta; Razelle Kurzrock
Journal:  Oncologist       Date:  2011-03-25

8.  Development of a fluorescent quantitative real-time polymerase chain reaction assay for the detection of Goose parvovirus in vivo.

Authors:  Jin-Long Yang; An-Chun Cheng; Ming-Shu Wang; Kang-Cheng Pan; Min Li; Yu-Fei Guo; Chuan-Feng Li; De-Kang Zhu; Xiao-Yue Chen
Journal:  Virol J       Date:  2009-09-15       Impact factor: 4.099

9.  Activity and mechanism of action of HDVD, a novel pyrimidine nucleoside derivative with high levels of selectivity and potency against gammaherpesviruses.

Authors:  N Coen; U Singh; V Vuyyuru; J J Van den Oord; J Balzarini; S Duraffour; R Snoeck; Y C Cheng; C K Chu; G Andrei
Journal:  J Virol       Date:  2013-01-23       Impact factor: 5.103

10.  Calibration technologies for correct determination of Epstein-Barr Virus, human herpesvirus 6 (HHV-6), and HHV-8 antiviral drug susceptibilities by use of real-time-PCR-based assays.

Authors:  Francesco Broccolo; Paolo Lusso; Mauro Malnati
Journal:  J Clin Microbiol       Date:  2013-06       Impact factor: 5.948
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