Literature DB >> 15128478

Leptin, sympathetic nervous system, and baroreflex function.

Guido Grassi1.   

Abstract

In addition to its direct effects on energy metabolism and caloric intake, leptin exerts several circulatory effects that appear to be mediated by an interaction with the sympathetic nervous system and the major reflexogenic area involved in cardiovascular homeostatic control--that is, the arterial baroreflex. In this paper, the relationships between the adipocyte hormone and the neuroadrenergic function are reviewed, taking into account data collected in experimental animal models as well as in human cardiovascular (hypertension and heart failure) and noncardiovascular (obesity) diseases that are characterized by a hyperadrenergic state coupled with a hyperleptinemia.

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Year:  2004        PMID： 15128478     DOI： 10.1007/s11906-004-0075-8

Source DB:  PubMed          Journal:  Curr Hypertens Rep        ISSN： 1522-6417            Impact factor:   5.369


  38 in total

1.  Central effects of leptin on cardiovascular and neurohormonal responses in conscious rabbits.

Authors:  K Matsumura; I Abe; T Tsuchihashi; M Fujishima
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2000-05       Impact factor: 3.619

2.  Plasma leptin concentrations and cardiac autonomic nervous system in healthy subjects with different body weights.

Authors:  G Paolisso; D Manzella; N Montano; A Gambardella; M Varricchio
Journal:  J Clin Endocrinol Metab       Date:  2000-05       Impact factor: 5.958

3.  Differential modulation of leptin-induced sympathoexcitation by baroreflex activation.

Authors:  Martin Hausberg; Donald A Morgan; Mark A Chapleau; William I Sivitz; Allyn L Mark; William G Haynes
Journal:  J Hypertens       Date:  2002-08       Impact factor: 4.844

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Authors:  D V Rayner; P Trayhurn
Journal:  J Mol Med (Berl)       Date:  2001       Impact factor: 4.599

Review 5.  Clinical review 94: What's in a name? In search of leptin's physiologic role.

Authors:  J S Flier
Journal:  J Clin Endocrinol Metab       Date:  1998-05       Impact factor: 5.958

6.  Interactions between the melanocortin system and leptin in control of sympathetic nerve traffic.

Authors:  W G Haynes; D A Morgan; A Djalali; W I Sivitz; A L Mark
Journal:  Hypertension       Date:  1999-01       Impact factor: 10.190

7.  Targeted disruption of the melanocortin-4 receptor results in obesity in mice.

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Journal:  Cell       Date:  1997-01-10       Impact factor: 41.582

8.  Body fat and sympathetic nerve activity in healthy subjects.

Authors:  U Scherrer; D Randin; L Tappy; P Vollenweider; E Jéquier; P Nicod
Journal:  Circulation       Date:  1994-06       Impact factor: 29.690

9.  Chronic leptin infusion increases arterial pressure.

Authors:  E W Shek; M W Brands; J E Hall
Journal:  Hypertension       Date:  1998-01       Impact factor: 10.190

10.  Dissociation between muscle and skin sympathetic nerve activity in essential hypertension, obesity, and congestive heart failure.

Authors:  G Grassi; M Colombo; G Seravalle; D Spaziani; G Mancia
Journal:  Hypertension       Date:  1998-01       Impact factor: 10.190
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  9 in total

Review 1.  Posttraumatic stress disorder: A metabolic disorder in disguise?

Authors:  Vasiliki Michopoulos; Aimee Vester; Gretchen Neigh
Journal:  Exp Neurol       Date:  2016-05-28       Impact factor: 5.330

2.  Neuroadrenergic and reflex abnormalities in patients with metabolic syndrome.

Authors:  G Grassi; R Dell'Oro; F Quarti-Trevano; F Scopelliti; G Seravalle; F Paleari; P L Gamba; G Mancia
Journal:  Diabetologia       Date:  2005-06-03       Impact factor: 10.122

3.  Autonomic nervous system function in women with anorexia nervosa.

Authors:  Zoe M Jenkins; David J Castle; Nina Eikelis; Andrea Phillipou; Gavin W Lambert; Elisabeth A Lambert
Journal:  Clin Auton Res       Date:  2021-11-11       Impact factor: 4.435

4.  Leptin acts in the forebrain to differentially influence baroreflex control of lumbar, renal, and splanchnic sympathetic nerve activity and heart rate.

Authors:  Baoxin Li; Zhigang Shi; Priscila A Cassaglia; Virginia L Brooks
Journal:  Hypertension       Date:  2013-02-19       Impact factor: 10.190

5.  Blunted sympathoinhibitory responses in obesity-related hypertension are due to aberrant central but not peripheral signalling mechanisms.

Authors:  Jackie M Y How; Suhail A Wardak; Shaik I Ameer; Rachel A Davey; Daniela M Sartor
Journal:  J Physiol       Date:  2014-02-03       Impact factor: 5.182

6.  The enhanced hyperglycemic response to hemorrhage hypotension in obese rats is related to an impaired baroreflex.

Authors:  Daniel Carvalho de Lima; Simonton Andrade Silveira; Andréa Siqueira Haibara; Cândido Celso Coimbra
Journal:  Metab Brain Dis       Date:  2008-10-03       Impact factor: 3.584

7.  Association of high blood pressure with body mass index, smoking and physical activity in healthy young adults.

Authors:  George Papathanasiou; Efthimia Zerva; Ioannis Zacharis; Maria Papandreou; Effie Papageorgiou; Christina Tzima; Dimitris Georgakopoulos; Angelos Evangelou
Journal:  Open Cardiovasc Med J       Date:  2015-02-27

8.  Sympathetic neural adaptation to hypocaloric diet with or without exercise training in obese metabolic syndrome subjects.

Authors:  Nora E Straznicky; Elisabeth A Lambert; Paul J Nestel; Mariee T McGrane; Tye Dawood; Markus P Schlaich; Kazuko Masuo; Nina Eikelis; Barbora de Courten; Justin A Mariani; Murray D Esler; Florentia Socratous; Reena Chopra; Carolina I Sari; Eldho Paul; Gavin W Lambert
Journal:  Diabetes       Date:  2009-10-15       Impact factor: 9.461

9.  Role of leptin receptor gene polymorphisms in susceptibility to the development of essential hypertension: a case-control association study in a Northern Han Chinese population.

Authors:  Y Liu; Y Q Lou; K Liu; J L Liu; Z G Wang; J Wen; Q Zhao; S J Wen; L Xiao
Journal:  J Hum Hypertens       Date:  2014-02-13       Impact factor: 3.012
  9 in total

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