| Literature DB >> 15128203 |
Michael Pircher1, Erich Goetzinger, Rainer Leitgeb, Christoph K Hitzenberger.
Abstract
We present a novel optical coherence tomography (OCT) method to measure backscattered intensity and birefringence properties (retardation and fast axis orientation) and apply it to imaging of human ocular tissue. The method is based on a Mach Zehnder interferometer, on transversal scanning, and on a polarization sensitive two-channel detection. A highly stable carrier frequency is generated by acousto-optic modulators (AOMs). This allows a phase sensitive demodulation by the lock-in technique. Since the recording of individual interference fringes is avoided by this method the amount of data to be recorded and processed is considerably reduced. We demonstrate this method on human cornea and anterior chamber angle and present, to the best of our knowledge, the first OCT images of retardation and fast axis orientation of the anterior chamber angle region in vivo.Entities:
Mesh:
Year: 2004 PMID: 15128203 DOI: 10.1088/0031-9155/49/7/013
Source DB: PubMed Journal: Phys Med Biol ISSN: 0031-9155 Impact factor: 3.609