Literature DB >> 15127181

Genetic polymorphisms of CYP1A1 in a Korean population.

Duk Woong Park1, Bohwan Jin, Dongdeuk Jang, Kihwa Yang, Jung-Duck Park, Yong-Soon Lee, Doug-Young Ryu.   

Abstract

Genetic polymorphisms in the coding exons of the CYP1A1 gene were analyzed in 100 Koreans. Three types of CYP1A1 polymorphisms, specifically G134A, G184C and A2455G, were identified with allelic frequencies of 18, 3, and 16%, respectively, and no linkage was observed among them. The novel G184C polymorphism identified in this study was associated with the mutation of an alanine residue at position 62 to proline. Other earlier-reported polymorphisms in the coding region of CYP1A1 were not detected.

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Year:  2004        PMID： 15127181     DOI： 10.1007/s00204-004-0552-5

Source DB:  PubMed          Journal:  Arch Toxicol        ISSN： 0340-5761            Impact factor:   5.153


  3 in total

1.  Mutation and protein expression analysis of CYP1A1 gene-a study on female breast cancer cases from India.

Authors:  Mohammad Zeeshan Najm; Salman Akhtar; Istaq Ahmad; Shilpi Chattopadhyay; Nasar Mallick; Sarah Siddiqui; Shuaib Zaidi; Waseem Ahmad Siddiqui; Syed Akhtar Husain
Journal:  Tumour Biol       Date:  2013-10-07

2.  Mutational analysis of xenobiotic metabolizing genes (CYP1A1 and GSTP1) in sporadic head and neck cancer patients.

Authors:  Nosheen Masood; Mahmood Akhtar Kayani
Journal:  Genet Mol Biol       Date:  2011-10-01       Impact factor: 1.771

3.  Association of the G134A and G184C Polymorphisms in the CYP1A1 Gene with Lung Cancer Incidence.

Authors:  Doug-Young Ryu; Mingai Huang; Changbo Park; Soo Im Chang; Ruth Im; Seong-Jin Choi; Na-Young Kim; In Won Park; Byoung Whui Choi; Jae Yeol Kim; Jong Wook Shin; Jae Chul Choi; Byung-Sun Choi; Jung-Duck Park
Journal:  Toxicol Res       Date:  2008-06-01
  3 in total

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