| Literature DB >> 15125974 |
Min Amy Xiang1, Robert H Chen, Keith T Demarest, Joseph Gunnet, Richard Look, William Hageman, William V Murray, Donald W Combs, Mona Patel.
Abstract
A novel series of spirobenzazepines was synthesized and evaluated for V1a and V2 receptor antagonist activity. Compounds 8b, 8i, and 8k have shown selective V1a receptor antagonist activity. Compounds 8p and 8q were shown to be dual V1a/V2 receptor antagonists.Entities:
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Year: 2004 PMID： 15125974 DOI： 10.1016/j.bmcl.2004.02.103
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823