| Literature DB >> 15125932 |
Lehua Deng1, Hao Wu, Biao Yu, Manrong Jiang, Jiarui Wu.
Abstract
Four analogs of OSW-1 (1-4) with modified side chains on the steroidal skeleton were synthesized following modification of our previous route for the total synthesis of OSW-1. Testing of the analogs against growth of tumor cells demonstrated that the 22-one function and the full length of the side chain of OSW-1 were not required for the antitumor action of OSW-1.Entities:
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Year: 2004 PMID： 15125932 DOI： 10.1016/j.bmcl.2004.03.081
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823