| Literature DB >> 15125923 |
Richard Chesworth1, Michael P Zawistoski, Bruce A Lefker, Kimberly O Cameron, Robert F Day, F Michael Mangano, Robert L Rosati, Stacy Colella, Donna N Petersen, Amy Brault, Bihong Lu, Lydia C Pan, Pia Perry, Oicheng Ng, Tessa A Castleberry, Thomas A Owen, Thomas A Brown, David D Thompson, Paul DaSilva-Jardine.
Abstract
Two series of 6-hydroxy and 7-hydroxy tetrahydroisoquinolines were prepared. Evaluating a range of C-1, C-4, and N-substituents led to the discovery of ER alpha and ER beta selective analogs.Entities:
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Year: 2004 PMID： 15125923 DOI： 10.1016/j.bmcl.2004.03.077
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823