OBJECTIVE: The goal of this study was to assess whether instituting a standard procedure to minimize transient activation prior to the subjective rating of sleepiness can improve the predictive value of the rating process. METHODS:Thirty young adults, aged 19 to 26 years, participated in the study. Subsequent to sleeping at home with bedtime restricted to 5 hours, they came to the sleep laboratory. They were instructed to rate their level of sleepiness on the Stanford Sleepiness Scale (SSS) and visual analog scales (VAS). A "calm-down" procedure, sitting quietly with eyes closed for 1 minute, was instituted prior to sleepiness ratings for half of the subjects (experimental group) but not for the other half of the subjects (control group). A nap trial with polysomnographic recording was then conducted, followed by a vigilance test. RESULTS: For the experimental group, VAS results of "sleepiness" and "alertness" both correlated significantly with sleep-onset latency during the nap (SOL: r = -.62 and .64, respectively, P values < .05) and with reaction time (RT) on the vigilance test (r = .56 and -.54, P values < .05). The SSS ratings showed significant correlation with nap SOL (r = -.58, P < .05) but not with RT on the vigilance test (r = .19, p = .52). For the control group, none of the subjective ratings showed significant correlation with objective measures. The differences between the resultant correlations for the 2 groups were statistically significant for 2 sets of correlations: the correlation between VAS of "alertness" and nap SOL and the correlation between VAS of "sleepiness" and RT on the vigilance test. CONCLUSION: The results indicate that the subjective ratings of the sleepiness state for individuals with mild sleep restriction more faithfully reflect a physiologic tendency to fall asleep as well as cognitive attentiveness when the ratings are conducted subsequent to sitting still with eyes closed for a sufficient time to minimize transient activation.
RCT Entities:
OBJECTIVE: The goal of this study was to assess whether instituting a standard procedure to minimize transient activation prior to the subjective rating of sleepiness can improve the predictive value of the rating process. METHODS: Thirty young adults, aged 19 to 26 years, participated in the study. Subsequent to sleeping at home with bedtime restricted to 5 hours, they came to the sleep laboratory. They were instructed to rate their level of sleepiness on the Stanford Sleepiness Scale (SSS) and visual analog scales (VAS). A "calm-down" procedure, sitting quietly with eyes closed for 1 minute, was instituted prior to sleepiness ratings for half of the subjects (experimental group) but not for the other half of the subjects (control group). A nap trial with polysomnographic recording was then conducted, followed by a vigilance test. RESULTS: For the experimental group, VAS results of "sleepiness" and "alertness" both correlated significantly with sleep-onset latency during the nap (SOL: r = -.62 and .64, respectively, P values < .05) and with reaction time (RT) on the vigilance test (r = .56 and -.54, P values < .05). The SSS ratings showed significant correlation with nap SOL (r = -.58, P < .05) but not with RT on the vigilance test (r = .19, p = .52). For the control group, none of the subjective ratings showed significant correlation with objective measures. The differences between the resultant correlations for the 2 groups were statistically significant for 2 sets of correlations: the correlation between VAS of "alertness" and nap SOL and the correlation between VAS of "sleepiness" and RT on the vigilance test. CONCLUSION: The results indicate that the subjective ratings of the sleepiness state for individuals with mild sleep restriction more faithfully reflect a physiologic tendency to fall asleep as well as cognitive attentiveness when the ratings are conducted subsequent to sitting still with eyes closed for a sufficient time to minimize transient activation.
Authors: Suzanne Ftouni; Shadab A Rahman; Kate E Crowley; Clare Anderson; Shantha M W Rajaratnam; Steven W Lockley Journal: J Biol Rhythms Date: 2013-12 Impact factor: 3.182