Literature DB >> 15123999

Brucellar spondylitis: a rare cause of spinal cord compression.

B Sonel Tur1, N Suldur, S Ataman, E A Ozturk, A Bingol, M B Atay.   

Abstract

STUDY
DESIGN: A case report.
OBJECTIVES: To present and discuss some of the difficulties in the diagnosis of brucellar spondylitis.
SETTING: Ankara University, Ibni Sina Hospital, Turkey.
METHODS: We report a patient with paraplegia, misdiagnosed as having a malignancy or tuberculosis who actually suffered from brucellar spondylitis. Diagnosis was established by her history and a compatible clinical picture together with a standard tube agglutination (Wright test) titer of > or =1/160 of antibodies for brucellosis. The patient was treated with oral doxycycline, rifampicin, and ciprofloxacin combination.
RESULTS: At the end of the treatment, the blood Brucella Wright and anti-human globulin T titer levels decreased. Her lower limb weakness improved. She could walk, and climb stairs with the help of a cane. Urinary retention and fecal incontinence also resolved.
CONCLUSION: Brucellosis is a systemic infection involving the musculoskeletal and nervous systems. Spondylitis frequently occurs in elderly patients. An early diagnosis of brucellar spondylitis can often be difficult. In endemic regions, as in the case of our country, brucellar spondylitis should always be considered in the differential diagnosis of older patients with back pain and constitutional symptoms. An early diagnosis will help to prevent the development of more severe complications such as spinal cord compression.

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Year:  2004        PMID: 15123999     DOI: 10.1038/sj.sc.3101571

Source DB:  PubMed          Journal:  Spinal Cord        ISSN: 1362-4393            Impact factor:   2.772


  3 in total

Review 1.  Quinolones for treatment of human brucellosis: critical review of the evidence from microbiological and clinical studies.

Authors:  Matthew E Falagas; Ioannis A Bliziotis
Journal:  Antimicrob Agents Chemother       Date:  2006-01       Impact factor: 5.191

Review 2.  Neuroimaging of infections.

Authors:  Oliver Kastrup; Isabel Wanke; Matthias Maschke
Journal:  NeuroRx       Date:  2005-04

3.  Could remembering the prozone phenomenon shorten our diagnostic journey in brucellosis? A case of Brucella spondylodiscitis.

Authors:  Gulay Sain Guven; Banu Cakir; Gul Oz; Mine Durusu Tanriover; Ercan Turkmen; Tumay Sozen
Journal:  Rheumatol Int       Date:  2006-02-17       Impact factor: 2.631

  3 in total

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