BACKGROUND: To evaluate the accuracy of fine-needle aspiration cytology (FNAC) in salivary gland lesions in a tertiary referral center. METHODS: A cytohistologic correlation study was performed using an automated pathology database of 1023 patients diagnosed with a salivary gland lesion. RESULTS: In 388 cases, both cytology and histology were available. Using cytologic confirmation of malignancy as the starting point, the sensitivity, specificity, and accuracy of FNAC in this study were 88%, 99%, and 96%, respectively. Exact type-specific concordance of the malignant diagnosis was achieved in 66 (88%) of 75 cases and in 211 (95%) of 223 benign cases. Of the 19 cases with a cytologic diagnosis "cyst," four proved to be malignant. A non-neoplastic lesion at cytology proved to be correctly classified in 53 (68%) of 80 patients. CONCLUSIONS: Our data show that cytology is a reliable and accurate technique to assess lesions of the salivary glands. The cytologic diagnosis of "cysts" and "non-neoplastic lesions" should be interpreted with caution. Copyright 2004 Wiley Periodicals, Inc. Head Neck 26: 418-424, 2004
BACKGROUND: To evaluate the accuracy of fine-needle aspiration cytology (FNAC) in salivary gland lesions in a tertiary referral center. METHODS: A cytohistologic correlation study was performed using an automated pathology database of 1023 patients diagnosed with a salivary gland lesion. RESULTS: In 388 cases, both cytology and histology were available. Using cytologic confirmation of malignancy as the starting point, the sensitivity, specificity, and accuracy of FNAC in this study were 88%, 99%, and 96%, respectively. Exact type-specific concordance of the malignant diagnosis was achieved in 66 (88%) of 75 cases and in 211 (95%) of 223 benign cases. Of the 19 cases with a cytologic diagnosis "cyst," four proved to be malignant. A non-neoplastic lesion at cytology proved to be correctly classified in 53 (68%) of 80 patients. CONCLUSIONS: Our data show that cytology is a reliable and accurate technique to assess lesions of the salivary glands. The cytologic diagnosis of "cysts" and "non-neoplastic lesions" should be interpreted with caution. Copyright 2004 Wiley Periodicals, Inc. Head Neck 26: 418-424, 2004
Authors: Miquel Quer; Vincent Vander Poorten; Robert P Takes; Carl E Silver; Carsten C Boedeker; Remco de Bree; Alessandra Rinaldo; Alvaro Sanabria; Ashok R Shaha; Albert Pujol; Peter Zbären; Alfio Ferlito Journal: Eur Arch Otorhinolaryngol Date: 2017-06-21 Impact factor: 2.503
Authors: Eric Barbarite; Sidharth V Puram; Adeeb Derakhshan; Esther D Rossi; William C Faquin; Mark A Varvares Journal: Laryngoscope Date: 2019-03-08 Impact factor: 3.325