| Literature DB >> 15121000 |
V González-Vélez1, J R Godínez-Fernández.
Abstract
We report the simulation of five C2+ regulation mechanisms in response to voltage-clamp pulses applied at the membrane. We obtain the currents generated and also record the C2+ concentration changes in the whole cell during and after the pulse. Our simulator includes models for the L-type voltage-dependent C2+ channels, the C2+ pump, the Na+/C2+ exchanger and a fast buffering system, along with diffusion assuming a spheric cell shape. Copyright 2003 Elsevier Ltd.Entities:
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Year: 2004 PMID： 15121000 DOI： 10.1016/S0010-4825(03)00071-4
Source DB: PubMed Journal: Comput Biol Med ISSN： 0010-4825 Impact factor: 4.589