Literature DB >> 15118316

Fractionation and anti-tumor activity of the mycelia of liquid-cultured Phellinus linteus.

Tomoyuki Nakamura1, Seiichi Matsugo, Yasuyuki Uzuka, Sumitaka Matsuo, Hirokazu Kawagishi.   

Abstract

All the fractions of Phellinus linteus mycelia showed anti-tumor activity toward solid tumors planted in mice. The highest anti-tumor activity of 81.2% was observed in the protein-glucan complex obtained by precipitating the 24% NaOH extract at pH 6.0. This protein-glucan complex consisted of 39.3% polysaccharide and 49.4% protein. Its (13)C- and (1)H-NMR data showed that the main glucan part of the complex was simple alpha-1,3-glucan chains.

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Year:  2004        PMID： 15118316     DOI： 10.1271/bbb.68.868

Source DB:  PubMed          Journal:  Biosci Biotechnol Biochem        ISSN： 0916-8451            Impact factor:   2.043


  13 in total

1.  Ethanol extract of Phellinus merrillii protects against diethylnitrosamine- and 2-acetylaminofluorene-induced hepatocarcinogenesis in rats.

Authors:  Chun-Hung Yang; Heng-Yuan Chang; Yi-Chuan Chen; Chia-Chen Lu; Shyh-Shyun Huang; Guan-Jhong Huang; Hsin-Chih Lai
Journal:  Chin J Integr Med       Date:  2016-08-02       Impact factor: 1.978

2.  Medicinal mushroom Phellinus linteus as an alternative cancer therapy.

Authors:  Daniel Sliva
Journal:  Exp Ther Med       Date:  2010-05-01       Impact factor: 2.447

3.  Structural analysis of glycogen-like polysaccharides having macrophage-activating activity in extracts of Lentinula edodes mycelia.

Authors:  Hiroaki Kojima; Junji Akaki; Satomi Nakajima; Kaeko Kamei; Makoto Tamesada
Journal:  J Nat Med       Date:  2009-08-27       Impact factor: 2.343

4.  Bioconversion of starch processing waste to Phellinus linteus mycelium in solid-state cultivation.

Authors:  Seungyong Lee; Hyokwan Bae; Minkyung Song; Seokhwan Hwang
Journal:  J Ind Microbiol Biotechnol       Date:  2008-04-22       Impact factor: 3.346

Review 5.  Antiinflammatory and immunomodulating properties of fungal metabolites.

Authors:  Cristina Lull; Harry J Wichers; Huub F J Savelkoul
Journal:  Mediators Inflamm       Date:  2005-06-09       Impact factor: 4.711

6.  Inhibition of IgE-dependent mouse triphasic cutaneous reaction by a boiling water fraction separated from mycelium of Phellinus linteus.

Authors:  Naoki Inagaki; Tomonori Shibata; Tomokazu Itoh; Tomohiro Suzuki; Hiroyuki Tanaka; Tomoyuki Nakamura; Yukihito Akiyama; Hirokazu Kawagishi; Hiroichi Nagai
Journal:  Evid Based Complement Alternat Med       Date:  2005-09       Impact factor: 2.629

7.  Extracellular polysaccharide production by a strain of Pleurotus djamor isolated in the south of Brazil and antitumor activity on Sarcoma 180.

Authors:  Gisele Martini Borges; Fabiana Figueredo Molin De Barba; Ana Paula Schiebelbein; Bruna Parmezzani Pereira; Mariane Bonatti Chaves; Marcia Luciane Lange Silveira; Mauro Souza Leite Pinho; Sandra Aparecida Furlan; Elisabeth Wisbeck
Journal:  Braz J Microbiol       Date:  2014-03-10       Impact factor: 2.476

8.  Ionone Derivatives from the Mycelium of Phellinus linteus and the Inhibitory Effect on Activated Rat Hepatic Stellate Cells.

Authors:  Shiow-Chyn Huang; Ping-Chung Kuo; Hsin-Yi Hung; Tai-Long Pan; Fu-An Chen; Tian-Shung Wu
Journal:  Int J Mol Sci       Date:  2016-05-06       Impact factor: 5.923

9.  Immunomodulatory effect of water soluble extract separated from mycelium of Phellinus linteus on experimental atopic dermatitis.

Authors:  Ji Sun Hwang; Ho-Keun Kwon; Jung-Eun Kim; Jeonghae Rho; Sin-Hyeog Im
Journal:  BMC Complement Altern Med       Date:  2012-09-18       Impact factor: 3.659

10.  Filtrate of Phellinus linteus Broth Culture Reduces Infarct Size Significantly in a Rat Model of Permanent Focal Cerebral Ischemia.

Authors:  Sakiko Suzuki; Takakazu Kawamata; Yoshikazu Okada; Tomonori Kobayashi; Tomoyuki Nakamura; Tomokatsu Hori
Journal:  Evid Based Complement Alternat Med       Date:  2011-04-06       Impact factor: 2.629
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