Literature DB >> 15113866

Acute myeloid leukaemia presenting as cholestatic hepatitis.

F A Wandroo1, J Murray, D Mutimer, S Hubscher.   

Abstract

A 40 year old man presented with abdominal pain, jaundice, weight loss, and hepatosplenomegaly. Liver function tests revealed cholestatic jaundice and a computed tomography scan showed an enlarged liver, with a normal biliary tree. Liver biopsy showed diffuse infiltration by neutrophils, monocytoid cells, and blasts. Peripheral blood film and bone marrow were consistent with acute myeloid leukaemia. After treatment with chemotherapy using an acute myeloid leukaemia protocol (UK Medical Research Council AML-12), there was complete resolution of jaundice and the patient went into complete molecular remission.

Entities:  

Mesh：

Year:  2004        PMID： 15113866      PMCID： PMC1770297          DOI： 10.1136/jcp.2003.013565

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN： 0021-9746            Impact factor:   3.411


  5 in total

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Journal:  Cancer       Date:  1987-07-01       Impact factor: 6.860

Review 4.  Acute leukemia presenting as jaundice with acute liver failure.

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Journal:  Clin Pediatr (Phila)       Date:  1973-12       Impact factor: 1.168

5.  World Health Organization classification of neoplastic diseases of the hematopoietic and lymphoid tissues: report of the Clinical Advisory Committee meeting-Airlie House, Virginia, November 1997.

Authors:  N L Harris; E S Jaffe; J Diebold; G Flandrin; H K Muller-Hermelink; J Vardiman; T A Lister; C D Bloomfield
Journal:  J Clin Oncol       Date:  1999-12       Impact factor: 44.544
  5 in total
  10 in total

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9.  Acute hepatitis-like presentation with cholestasis of CBFB-MYH11-positive acute myeloid leukemia in an adult male: a case report.

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10.  Acute myeloid leukemia presenting as acute appendicitis.

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  10 in total

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