Literature DB >> 15113353

Organ donation and utilization in the USA.

Akinlolu O Ojo1, Dennis Heinrichs, Jean C Emond, Joshua J McGowan, Mary K Guidinger, Francis L Delmonico, Robert A Metzger.   

Abstract

The processes leading to donor identification, consent, organ procurement, and allocation continue to dominate debates and efforts in the field of transplantation. A considerable shortage of donors remains while the number of patients needing organ transplantation increases. This article reviews the main trends in organ donation practices and procurement patterns from both deceased and living sources in the USA. Although there have been increases in living donation in recent years, 2002 witnessed a much more modest growth of 1%. Absolute declines in living liver and lung donation were also noted in 2002. In 2002, the number of deceased donors increased by only 1.6% (101 donors). Increased donation from deceased donors provides more organs for transplantation than a comparable increase in living donation, because on average 3.6 organs are recovered from each deceased donor. The total number of organs recovered from deceased donors increased by 2.1% (462 organs). Poor organ quality continued to be the major reason given for nonrecovery of consented organs from deceased donors. The kidney is the organ most likely to be discarded after recovery. Over the past decade the discard rate of recovered kidneys has increased from 6% to 11%. Many of these are expanded criteria donor kidneys.

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Year:  2004        PMID: 15113353     DOI: 10.1111/j.1600-6135.2004.00396.x

Source DB:  PubMed          Journal:  Am J Transplant        ISSN: 1600-6135            Impact factor:   8.086


  14 in total

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Journal:  J Pediatr       Date:  2006-05       Impact factor: 4.406

2.  Racial and socioeconomic disparities in the allocation of expanded criteria donor kidneys.

Authors:  Rajesh Mohandas; Michael J Casey; Robert L Cook; Kenneth E Lamb; Xuerong Wen; Mark S Segal
Journal:  Clin J Am Soc Nephrol       Date:  2013-10-10       Impact factor: 8.237

Review 3.  East-West differences in perception of brain death. Review of history, current understandings, and directions for future research.

Authors:  Qing Yang; Geoffrey Miller
Journal:  J Bioeth Inq       Date:  2014-07-24       Impact factor: 1.352

4.  The 4G/4G genotype of the PAI-1 (serpine-1) 4G/5G polymorphism is associated with decreased lung allograft utilization.

Authors:  A Sapru; J G Zaroff; L Pawlikowska; K D Liu; K K Khush; L A Baxter-Lowe; V Hayden; R L Menza; M Convery; V Lo; A Poon; H Kim; W L Young; J Kukreja; M A Matthay
Journal:  Am J Transplant       Date:  2012-03-05       Impact factor: 8.086

5.  Single-nucleotide polymorphisms in the β-adrenergic receptor genes are associated with lung allograft utilization.

Authors:  Anil Sapru; Ludmila Pawlikowska; Kathleen D Liu; Kiran K Khush; Lee Ann-Baxter-Lowe; Vanessa Hayden; Rebecca L Menza; Maureen Convery; Annie Poon; Megan Landeck; Jonathan G Zaroff; Michael A Matthay
Journal:  J Heart Lung Transplant       Date:  2011-02       Impact factor: 10.247

6.  Advancing donor management research: design and implementation of a large, randomized, placebo-controlled trial.

Authors:  Lorraine B Ware; Tatsuki Koyama; Dean Billheimer; Megan Landeck; Elizabeth Johnson; Sandra Brady; Gordon R Bernard; Michael A Matthay
Journal:  Ann Intensive Care       Date:  2011-06-14       Impact factor: 6.925

Review 7.  Consent to organ donation: a review.

Authors:  Laura A Siminoff; Amma A Agyemang; Heather M Traino
Journal:  Prog Transplant       Date:  2013-03       Impact factor: 1.187

8.  Deceased Brain Dead Donor Liver Transplantation and Utilization in the United States: Nighttime and Weekend Effects.

Authors:  Dustin J Carpenter; Mariana C Chiles; Elizabeth C Verna; Karim J Halazun; Jean C Emond; Lloyd E Ratner; Sumit Mohan
Journal:  Transplantation       Date:  2019-07       Impact factor: 4.939

9.  A randomized trial of the effects of nebulized albuterol on pulmonary edema in brain-dead organ donors.

Authors:  L B Ware; M Landeck; T Koyama; Z Zhao; J Singer; R Kern; N Neidlinger; J Nguyen; E Johnson; D R Janz; G R Bernard; J W Lee; M A Matthay
Journal:  Am J Transplant       Date:  2014-03       Impact factor: 8.086

Review 10.  Persufflation (gaseous oxygen perfusion) as a method of heart preservation.

Authors:  Thomas M Suszynski; Michael D Rizzari; William E Scott; Peter M Eckman; James D Fonger; Ranjit John; Nicolas Chronos; Linda A Tempelman; David E R Sutherland; Klearchos K Papas
Journal:  J Cardiothorac Surg       Date:  2013-04-22       Impact factor: 1.637

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