Literature DB >> 15113101

Implications of new proteomics strategies for biology and medicine.

Bruno Domon1, Samuel Broder.   

Abstract

Advances in proteomics have fundamentally changed the paradigm of discovery for drug targets and novel biomarkers. Proteomics methodologies currently used will be reviewed in this paper, including structural proteomics, quantitative proteomics, and functional proteomics. A strategy to identify differentially expressed cell surface proteins as monoclonal therapeutic targets in oncology will be discussed.

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Year:  2004        PMID: 15113101     DOI: 10.1021/pr034082c

Source DB:  PubMed          Journal:  J Proteome Res        ISSN: 1535-3893            Impact factor:   4.466


  6 in total

1.  Options and considerations when selecting a quantitative proteomics strategy.

Authors:  Bruno Domon; Ruedi Aebersold
Journal:  Nat Biotechnol       Date:  2010-07-09       Impact factor: 54.908

2.  Prediction of the location of stationary steady-state zone positions in counterflow isotachophoresis performed under constant voltage in a vortex-stabilized annular column.

Authors:  Schurie L M Harrison; Cornelius F Ivory
Journal:  J Sep Sci       Date:  2007-12       Impact factor: 3.645

3.  An integrated, directed mass spectrometric approach for in-depth characterization of complex peptide mixtures.

Authors:  Alexander Schmidt; Nils Gehlenborg; Bernd Bodenmiller; Lukas N Mueller; Dave Campbell; Markus Mueller; Ruedi Aebersold; Bruno Domon
Journal:  Mol Cell Proteomics       Date:  2008-05-29       Impact factor: 5.911

4.  An optimal protocol to analyze the rat spinal cord proteome.

Authors:  F Gil-Dones; S Alonso-Orgaz; G Avila; T Martin-Rojas; V Moral-Darde; G Barroso; F Vivanco; J Scott-Taylor; M G Barderas
Journal:  Biomark Insights       Date:  2009-10-28

5.  Full dynamic range proteome analysis of S. cerevisiae by targeted proteomics.

Authors:  Paola Picotti; Bernd Bodenmiller; Lukas N Mueller; Bruno Domon; Ruedi Aebersold
Journal:  Cell       Date:  2009-08-06       Impact factor: 41.582

6.  Physicochemical Property Correlations with Ionization Efficiency in Capillary Vibrating Sharp-Edge Spray Ionization (cVSSI).

Authors:  Kinkini Udara Jayasundara; Chong Li; Anthony DeBastiani; Daud Sharif; Peng Li; Stephen J Valentine
Journal:  J Am Soc Mass Spectrom       Date:  2020-08-28       Impact factor: 3.109

  6 in total

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