Literature DB >> 15112959

New beauvericins, potentiators of antifungal miconazole activity, Produced by Beauveria sp. FKI-1366. I. Taxonomy, fermentation, isolation and biological properties.

Takashi Fukuda1, Masayoshi Arai, Yuichi Yamaguchi, Rokurou Masuma, Hiroshi Tomoda, Satoshi Omura.   

Abstract

Three new beauvericins, designated beauvericins D, E and F, were isolated along with known beauvericin and beauvericin A, from the culture of Beauveria sp. FKI-1366 by solvent extraction, ODS column chromatography and HPLC. These compounds potentiate miconazole activity against not only wild Candida albicans but also fluconazole resistant C. albicans. Beauvericins D and E decreased the IC50 value of miconazole against fluconazole resistant C. albicans from 1.3 microM to 0.25 and 0.31 microM, respectively.

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Year:  2004        PMID： 15112959     DOI： 10.7164/antibiotics.57.110

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  8 in total

1.  High-throughput synergy screening identifies microbial metabolites as combination agents for the treatment of fungal infections.

Authors:  Lixin Zhang; Kezhi Yan; Yu Zhang; Ren Huang; Jiang Bian; Chuansen Zheng; Haixiang Sun; Zhihui Chen; Nuo Sun; Rong An; Fangui Min; Weibo Zhao; Ying Zhuo; Jianlan You; Yongjie Song; Zhenyan Yu; Zhiheng Liu; Keqian Yang; Hong Gao; Huanqin Dai; Xiaoli Zhang; Jian Wang; Chengzhang Fu; Gang Pei; Jintao Liu; Si Zhang; Michael Goodfellow; Yuanying Jiang; Jun Kuai; Guochun Zhou; Xiaoping Chen
Journal:  Proc Natl Acad Sci U S A       Date:  2007-03-05       Impact factor: 11.205

2.  Detection of inhibitors of Candida albicans Cdr transporters using a diS-C3(3) fluorescence.

Authors:  Joanna Szczepaniak; Marcin Łukaszewicz; Anna Krasowska
Journal:  Front Microbiol       Date:  2015-03-09       Impact factor: 5.640

Review 3.  Beauvericin, a bioactive compound produced by fungi: a short review.

Authors:  Qinggui Wang; Lijian Xu
Journal:  Molecules       Date:  2012-02-24       Impact factor: 4.411

Review 4.  A Review on the Synthesis and Bioactivity Aspects of Beauvericin, a Fusarium Mycotoxin.

Authors:  Qinghua Wu; Jiri Patocka; Eugenie Nepovimova; Kamil Kuca
Journal:  Front Pharmacol       Date:  2018-11-20       Impact factor: 5.810

5.  Comparative Structure-Activity Analysis of the Antimicrobial Activity, Cytotoxicity, and Mechanism of Action of the Fungal Cyclohexadepsipeptides Enniatins and Beauvericin.

Authors:  Hamza Olleik; Cendrine Nicoletti; Mickael Lafond; Elise Courvoisier-Dezord; Peiwen Xue; Akram Hijazi; Elias Baydoun; Josette Perrier; Marc Maresca
Journal:  Toxins (Basel)       Date:  2019-09-03       Impact factor: 4.546

6.  Evidence for Naturally Produced Beauvericins Containing N-Methyl-Tyrosine in Hypocreales Fungi.

Authors:  Monika Urbaniak; Łukasz Stępień; Silvio Uhlig
Journal:  Toxins (Basel)       Date:  2019-03-26       Impact factor: 4.546

Review 7.  Fusarium Cyclodepsipeptide Mycotoxins: Chemistry, Biosynthesis, and Occurrence.

Authors:  Monika Urbaniak; Agnieszka Waśkiewicz; Łukasz Stępień
Journal:  Toxins (Basel)       Date:  2020-12-03       Impact factor: 4.546

8.  Beauvericin counteracted multi-drug resistant Candida albicans by blocking ABC transporters.

Authors:  Yaojun Tong; Mei Liu; Yu Zhang; Xueting Liu; Ren Huang; Fuhang Song; Huanqin Dai; Biao Ren; Nuo Sun; Gang Pei; Jiang Bian; Xin-Ming Jia; Guanghua Huang; Xuyu Zhou; Shaojie Li; Buchang Zhang; Takashi Fukuda; Hiroshi Tomoda; Satoshi Ōmura; Richard D Cannon; Richard Calderone; Lixin Zhang
Journal:  Synth Syst Biotechnol       Date:  2016-10-25
  8 in total

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