Literature DB >> 1511235

Dynamic properties of salmon calcitonin bound to sodium dodecyl sulfate micelles: a restrained molecular dynamics study from NMR data.

M A Castiglione Morelli1, A Pastore, A Motta.   

Abstract

We have investigated the conformational behaviour of salmon calcitonin bound to sodium dodecyl sulfate micelles by means of restrained molecular dynamics simulations with both 'static' and time-averaged NMR distance restraints. A more realistic picture of the inherent flexibility of the hormone is obtained when using time averaging. With this approach, long-range NOEs are interpreted better by considering a dynamical exchange among different conformations.

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Year:  1992        PMID： 1511235     DOI： 10.1007/bf01874812

Source DB:  PubMed          Journal:  J Biomol NMR        ISSN： 0925-2738            Impact factor:   2.835


  18 in total

1.  WHAT IF: a molecular modeling and drug design program.

Authors:  G Vriend
Journal:  J Mol Graph       Date:  1990-03

2.  Refinement of the NMR solution structure of a protein to remove distortions arising from neglect of internal motion.

Authors:  J Fejzo; A M Krezel; W M Westler; S Macura; J L Markley
Journal:  Biochemistry       Date:  1991-04-23       Impact factor: 3.162

3.  Time-averaged nuclear Overhauser effect distance restraints applied to tendamistat.

Authors:  A E Torda; R M Scheek; W F van Gunsteren
Journal:  J Mol Biol       Date:  1990-07-05       Impact factor: 5.469

Review 4.  Peptides from the calcitonin genes: molecular genetics, structure and function.

Authors:  L H Breimer; I MacIntyre; M Zaidi
Journal:  Biochem J       Date:  1988-10-15       Impact factor: 3.857

5.  A dynamic model for the structure of acyl carrier protein in solution.

Authors:  Y Kim; J H Prestegard
Journal:  Biochemistry       Date:  1989-10-31       Impact factor: 3.162

6.  A conformational study of porcine thyrocalcitonin.

Authors:  H B Brewer; H Edelhoch
Journal:  J Biol Chem       Date:  1970-05-10       Impact factor: 5.157

7.  Use of fully deuterated micelles for conformational studies of membrane proteins by high resolution 1H nuclear magnetic resonance.

Authors:  L R Brown
Journal:  Biochim Biophys Acta       Date:  1979-10-19

8.  Solution conformation of salmon calcitonin in sodium dodecyl sulfate micelles as determined by two-dimensional NMR and distance geometry calculations.

Authors:  A Motta; A Pastore; N A Goud; M A Castiglione Morelli
Journal:  Biochemistry       Date:  1991-10-29       Impact factor: 3.162

9.  Conformations of model peptides in membrane-mimetic environments.

Authors:  L M Gierasch; J E Lacy; K F Thompson; A L Rockwell; P I Watnick
Journal:  Biophys J       Date:  1982-01       Impact factor: 4.033

10.  Two-dimensional NMR and structure determination of salmon calcitonin in methanol.

Authors:  R P Meadows; E P Nikonowicz; C R Jones; J W Bastian; D G Gorenstein
Journal:  Biochemistry       Date:  1991-02-05       Impact factor: 3.162
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  4 in total

1.  Conformational flexibility in calcitonin: the dynamic properties of human and salmon calcitonin in solution.

Authors:  P Amodeo; A Motta; G Strazzullo; M A Castiglione Morelli
Journal:  J Biomol NMR       Date:  1999-02       Impact factor: 2.835

2.  Converting the highly amyloidogenic human calcitonin into a powerful fibril inhibitor by three-dimensional structure homology with a non-amyloidogenic analogue.

Authors:  Giuseppina Andreotti; Rosa Maria Vitale; Carmit Avidan-Shpalter; Pietro Amodeo; Ehud Gazit; Andrea Motta
Journal:  J Biol Chem       Date:  2010-11-15       Impact factor: 5.157

3.  Macromolecular structural elucidation with solid-state NMR-derived orientational constraints.

Authors:  R R Ketchem; K C Lee; S Huo; T A Cross
Journal:  J Biomol NMR       Date:  1996-07       Impact factor: 2.835

4.  Three-dimensional structure and orientation of rat islet amyloid polypeptide protein in a membrane environment by solution NMR spectroscopy.

Authors:  Ravi Prakash Reddy Nanga; Jeffrey R Brender; Jiadi Xu; Kevin Hartman; Vivekanandan Subramanian; Ayyalusamy Ramamoorthy
Journal:  J Am Chem Soc       Date:  2009-06-17       Impact factor: 15.419
  4 in total

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