Literature DB >> 15111740

Role of the nonhuman primate for research related to women's health.

David F Archer1.   

Abstract

This overview of the current status of medical problems that affect women is related to current studies on pathophysiology and therapeutic interventions using nonhuman primates to demonstrate the utility of the primate model for the study of disease processes in women. The current medical literature on women's health is compared with the literature on nonhuman primate research. The findings reviewed in the articles of ILAR Journal Volume 45 Issue 2 of 2004 are evaluated in the context of the scope and problems associated with disease entities in women. Nonhuman primate research with known information regarding women's disease is discussed, and the utility of the animal model for the study of human disease is highlighted, based on its significant relevance due to similarities of nonhuman primate and human subjects' physiology, metabolism, and responses to therapeutic interventions. Additional advantages of the animal model include the ability to control the experimental environment and the capacity to perform chronic study procedures. These findings allow us to utilize the nonhuman primate as the most relevant model in the animal world for the study of human disease processes.

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Year:  2004        PMID: 15111740     DOI: 10.1093/ilar.45.2.212

Source DB:  PubMed          Journal:  ILAR J        ISSN: 1084-2020


  7 in total

1.  The effects of bazedoxifene in the ovariectomized aged cynomolgus monkey.

Authors:  Susan Y Smith; Jacquelin Jolette; Luc Chouinard; Barry S Komm
Journal:  J Bone Miner Metab       Date:  2014-03-16       Impact factor: 2.626

2.  G-protein coupled estrogen receptor, estrogen receptor α, and progesterone receptor immunohistochemistry in the hypothalamus of aging female rhesus macaques given long-term estradiol treatment.

Authors:  Michelle M Naugle; Long T Nguyen; Tyler K Merceron; Edward Filardo; William G M Janssen; John H Morrison; Peter R Rapp; Andrea C Gore
Journal:  J Exp Zool A Ecol Genet Physiol       Date:  2014-05-24

3.  Physiology and Endocrinology of the Ovarian Cycle in Macaques.

Authors:  Gerhard F Weinbauer; Marc Niehoff; Michael Niehaus; Shiela Srivastav; Antje Fuchs; Eric Van Esch; J Mark Cline
Journal:  Toxicol Pathol       Date:  2008-12       Impact factor: 1.902

4.  Effect of pre-freezing conditions on semen cryopreservation in rhesus monkeys.

Authors:  Q Dong; S E Rodenburg; C Huang; C A VandeVoort
Journal:  Theriogenology       Date:  2008-04-22       Impact factor: 2.740

5.  Species Comparison of the Role of p38 MAP Kinase in the Female Reproductive System.

Authors:  Zaher A Radi; Rosemary A Marusak; Dale L Morris
Journal:  J Toxicol Pathol       Date:  2009-07-07       Impact factor: 1.628

6.  Strategies for using the sheep ovarian cortex as a model in reproductive medicine.

Authors:  Maïté Fransolet; Soraya Labied; Laurie Henry; Marie-Caroline Masereel; Eric Rozet; Nathalie Kirschvink; Michelle Nisolle; Carine Munaut
Journal:  PLoS One       Date:  2014-03-10       Impact factor: 3.240

7.  Relationship between menarche and fertility in long-tailed macaques (Macaca fascicularis).

Authors:  Maiko Kobayashi; Takamasa Koyama; Yasuhiro Yasutomi; Tadashi Sankai
Journal:  J Reprod Dev       Date:  2018-05-31       Impact factor: 2.214

  7 in total

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