Literature DB >> 15111682

Paraneoplastic "stiff person syndrome" with metastatic adenocarcinoma and anti-Ri antibodies.

D J H McCabe1, N C Turner, D Chao, A Leff, N A Gregson, H J Womersley, I Mak, G D Perkin, A H V Schapira.   

Abstract

A 43-year-old woman presented with clinical and electrophysiologic features of stiff person syndrome (SPS), without abdominal or lumbar paraspinal muscle involvement. Investigations revealed metastatic adenocarcinoma of the lung with positive anti-Ri antibodies. Her clinical condition improved with diazepam, baclofen, tizanidine, and palliative chemotherapy. Screening for an underlying malignancy and anti-Ri antibodies should be considered in patients with SPS when clinical presentation is atypical.

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Year:  2004        PMID: 15111682     DOI: 10.1212/01.wnl.0000123694.64121.d5

Source DB:  PubMed          Journal:  Neurology        ISSN: 0028-3878            Impact factor:   9.910


  7 in total

Review 1.  Autoimmune stiff person syndrome and related myelopathies: understanding of electrophysiological and immunological processes.

Authors:  Goran Rakocevic; Mary Kay Floeter
Journal:  Muscle Nerve       Date:  2012-05       Impact factor: 3.217

2.  Stiff-arm syndrome.

Authors:  Enrique Urrea-Mendoza; Daniel Kanter; Fredy J Revilla; Eric Dornoff; Alberto J Espay
Journal:  Neurology       Date:  2015-09-22       Impact factor: 9.910

3.  An uncommon paraneoplastic Ri-positive opsoclonus-myoclonus-like syndrome and stiff-person syndrome with elevated glutamate/GABA ratio in the cerebrospinal fluid after breast cancer.

Authors:  A Thümen; A Moser
Journal:  J Neurol       Date:  2010-02-23       Impact factor: 4.849

4.  Paraneoplastic opsoclonus-myoclonus ataxia associated with non-small-cell lung carcinoma.

Authors:  Kiran Musunuru; Santosh Kesari
Journal:  J Neurooncol       Date:  2008-07-11       Impact factor: 4.130

5.  [Stiff man syndrome and variants].

Authors:  H-M Meinck
Journal:  Nervenarzt       Date:  2013-04       Impact factor: 1.214

Review 6.  Paraneoplastic movement disorders.

Authors:  Shyamal H Mehta; John C Morgan; Kapil D Sethi
Journal:  Curr Neurol Neurosci Rep       Date:  2009-07       Impact factor: 5.081

7.  Stiff-person syndrome with paraneoplastic neurological syndrome: a case report and literature review.

Authors:  Hanwen Zhang; Wenshi Wei
Journal:  Am J Transl Res       Date:  2022-02-15       Impact factor: 4.060

  7 in total

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