BACKGROUND: Previous analyses of lung cancer mortality were based on models of death rates within one time period, assuming that rates increase or decrease with time at a constant rate. The aim of this work is to analyse recent changes in lung cancer mortality trends in Andalusia (Spain) during the period of 1975-2000 using joinpoint regression models. PATIENTS AND METHODS: Mortality data were obtained from the Death Registry of Andalusia. For each gender, age group-specific and standardised (overall and truncated) rates were calculated by the direct method (using the world standard population). The joinpoint analysis was used to identify the best-fitting points where a statistically significant change in the trend occurred. RESULTS: Lung cancer is the leading cause of cancer mortality in men, with an increasing trend up to 1994. After that year, rates began to decrease significantly (-1.8% yearly from 1994 to 2000). Standardised rates in women exhibited a downward trend until the early 1990s, after which they levelled off (overall standardised rates) or increased significantly (truncated rates 35-64 years). CONCLUSIONS: An increase in lung cancer mortality has been observed in young women. There seems to be a relationship with the prevalence in smoking in men and women.
BACKGROUND: Previous analyses of lung cancer mortality were based on models of death rates within one time period, assuming that rates increase or decrease with time at a constant rate. The aim of this work is to analyse recent changes in lung cancer mortality trends in Andalusia (Spain) during the period of 1975-2000 using joinpoint regression models. PATIENTS AND METHODS: Mortality data were obtained from the Death Registry of Andalusia. For each gender, age group-specific and standardised (overall and truncated) rates were calculated by the direct method (using the world standard population). The joinpoint analysis was used to identify the best-fitting points where a statistically significant change in the trend occurred. RESULTS:Lung cancer is the leading cause of cancer mortality in men, with an increasing trend up to 1994. After that year, rates began to decrease significantly (-1.8% yearly from 1994 to 2000). Standardised rates in women exhibited a downward trend until the early 1990s, after which they levelled off (overall standardised rates) or increased significantly (truncated rates 35-64 years). CONCLUSIONS: An increase in lung cancer mortality has been observed in young women. There seems to be a relationship with the prevalence in smoking in men and women.
Authors: Jose P Zevallos; Jennifer R Kramer; Vlad C Sandulache; Sean T Massa; Christine M Hartman; Angela L Mazul; Benjamin M Wahle; Sophie P Gerndt; Erich M Sturgis; Elizabeth Y Chiao Journal: Head Neck Date: 2020-09-12 Impact factor: 3.821
Authors: Keith H Carter; Prabhjot Singh; Oscar J Mujica; Rainier P Escalada; Maria Paz Ade; Luis Gerardo Castellanos; Marcos A Espinal Journal: Am J Trop Med Hyg Date: 2014-12-29 Impact factor: 2.345