OBJECTIVE: To present three cases of primary Hypothyroidism with an atypical beginning. DESIGN: Retrospective clinical observations. SITE. Health Centre (Primary Care). PATIENTS OR OTHERS PARTICIPANTS: Three women (aged 38, 43 and 51) who were studied in the consulting room: one who presented Macrocytosis and Hypercholesterolemia; the second, a bilateral palpebral oedema; and the third, dysfonia unaccompanied by any other symptom of Hypothyroidism. MAIN MEASUREMENTS AND RESULTS: In the three cases, hypercholesterolemia was objectified, I4 diminished and TSH raised; in one of them T3 was normal, while it was low in the remainder. CONCLUSIONS: The alteracions observed are frequent in primary Hypothyroidism. But it is rare to find them on their own in the presentation of the clinical picture. Given this pathology's high prevalence, it is important to think of the pathology when presented with these atypical symptoms, and possibly to request the determination of TSH in isolation.
OBJECTIVE: To present three cases of primary Hypothyroidism with an atypical beginning. DESIGN: Retrospective clinical observations. SITE. Health Centre (Primary Care). PATIENTS OR OTHERS PARTICIPANTS: Three women (aged 38, 43 and 51) who were studied in the consulting room: one who presented Macrocytosis and Hypercholesterolemia; the second, a bilateral palpebral oedema; and the third, dysfonia unaccompanied by any other symptom of Hypothyroidism. MAIN MEASUREMENTS AND RESULTS: In the three cases, hypercholesterolemia was objectified, I4 diminished and TSH raised; in one of them T3 was normal, while it was low in the remainder. CONCLUSIONS: The alteracions observed are frequent in primary Hypothyroidism. But it is rare to find them on their own in the presentation of the clinical picture. Given this pathology's high prevalence, it is important to think of the pathology when presented with these atypical symptoms, and possibly to request the determination of TSH in isolation.
Authors: Paloma Domínguez Ruiz de León; Victoria Morcillo Cebolla; Blanca Gutiérrez Parres; Francisco Javier Cirujano Pita; Elvira Díaz de Tuesta Díaz de Lezama; Elena Mazorra Benito Journal: Aten Primaria Date: 2010-07-08 Impact factor: 1.137