Literature DB >> 15111108

Heavier-than-air flying machines are impossible.

L Oliveira1, T Hulsen, D Lutje Hulsik, A C M Paiva, G Vriend.   

Abstract

Many G protein-coupled receptor (GPCR) models have been built over the years. The release of the structure of bovine rhodopsin in August 2000 enabled us to analyze models built before that period to learn more about the models we build today. We conclude that the GPCR modelling field is riddled with 'common knowledge' similar to Lord Kelvin's remark in 1895 that "heavier-than-air flying machines are impossible", and we summarize what we think are the (im)possibilities of modelling GPCRs using the coordinates of bovine rhodopsin as a template. Associated WWW pages: www.gpcr.org/articles/2003_mod

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Year:  2004        PMID： 15111108     DOI： 10.1016/S0014-5793(04)00320-5

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  13 in total

1.  Interactions of human melanocortin 4 receptor with nonpeptide and peptide agonists.

Authors:  Irina D Pogozheva; Biao-Xin Chai; Andrei L Lomize; Tung M Fong; David H Weinberg; Ravi P Nargund; Michael W Mulholland; Ira Gantz; Henry I Mosberg
Journal:  Biochemistry       Date:  2005-08-30       Impact factor: 3.162

2.  A combined ligand-based and target-based drug design approach for G-protein coupled receptors: application to salvinorin A, a selective kappa opioid receptor agonist.

Authors:  Nidhi Singh; Gwénaël Chevé; David M Ferguson; Christopher R McCurdy
Journal:  J Comput Aided Mol Des       Date:  2006-09-29       Impact factor: 3.686

3.  How a small change in retinal leads to G-protein activation: initial events suggested by molecular dynamics calculations.

Authors:  Paul S Crozier; Mark J Stevens; Thomas B Woolf
Journal:  Proteins       Date:  2007-02-15

Review 4.  Biophysical dissection of membrane proteins.

Authors:  Stephen H White
Journal:  Nature       Date:  2009-05-21       Impact factor: 49.962

5.  Developing a high-quality scoring function for membrane protein structures based on specific inter-residue interactions.

Authors:  Andrew J Heim; Zhijun Li
Journal:  J Comput Aided Mol Des       Date:  2012-03-01       Impact factor: 3.686

6.  Structural model of ligand-G protein-coupled receptor (GPCR) complex based on experimental double mutant cycle data: MT7 snake toxin bound to dimeric hM1 muscarinic receptor.

Authors:  Catherine Marquer; Carole Fruchart-Gaillard; Guillaume Letellier; Elodie Marcon; Gilles Mourier; Sophie Zinn-Justin; André Ménez; Denis Servent; Bernard Gilquin
Journal:  J Biol Chem       Date:  2011-06-17       Impact factor: 5.157

7.  Integrating GPCR-specific information with full text articles.

Authors:  Bas Vroling; David Thorne; Philip McDermott; Teresa K Attwood; Gert Vriend; Steve Pettifer
Journal:  BMC Bioinformatics       Date:  2011-09-12       Impact factor: 3.307

Review 8.  Cardiovascular effects of losartan and its relevant clinical application.

Authors:  Feichao Xu; Caiping Mao; Yali Hu; Can Rui; Zhice Xu; Lubo Zhang
Journal:  Curr Med Chem       Date:  2009       Impact factor: 4.530

9.  Comparative sequence and structural analyses of G-protein-coupled receptor crystal structures and implications for molecular models.

Authors:  Catherine L Worth; Gunnar Kleinau; Gerd Krause
Journal:  PLoS One       Date:  2009-09-16       Impact factor: 3.240

Review 10.  Homology modelling and spectroscopy, a never-ending love story.

Authors:  Hanka Venselaar; Robbie P Joosten; Bas Vroling; Coos A B Baakman; Maarten L Hekkelman; Elmar Krieger; Gert Vriend
Journal:  Eur Biophys J       Date:  2009-08-29       Impact factor: 1.733
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