| Literature DB >> 15109966 |
Janko Nikolich-Zugich1, Daved H Fremont, Michael J Miley, Ilhem Messaoudi.
Abstract
The major histocompatibility complex (mhc)-encoded MHC class I and class II molecules present peptide fragments to T cells at every stage of their life (development, survival, persistence and activation). Thereby, these unusually polymorphic molecules critically influence susceptibility to autoimmune and infectious diseases. Here, we examine the mechanistic relationship between mhc polymorphism and anti-microbial resistance/susceptibility.Entities:
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Year: 2004 PMID： 15109966 DOI： 10.1016/j.micinf.2004.01.006
Source DB: PubMed Journal: Microbes Infect ISSN： 1286-4579 Impact factor: 2.700