Literature DB >> 1510995

What we can learn from the effects of thiol reagents on transport proteins.

P R van Iwaarden1, A J Driessen, W N Konings.   

Abstract

Many secondary membrane transport systems contain reactive sulfhydryl groups. In this review the applications of SH reagents for analyzing the role of sulfhydryl groups in membrane transport systems will be discussed. First an overview will be given of the more important reagents, that have been used to study SH-groups in membrane transport systems, and examples will be given of transport proteins in which the role of cysteines have been analyzed. An important application of SH-reagents to label transport proteins using various SH-reagents modified with fluorescent- or spin-label moieties will be discussed. Two general models are shown which have been proposed to explain the role of sulfhydryl groups in some membrane transport systems.

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Year:  1992        PMID： 1510995     DOI： 10.1016/0304-4157(92)90037-b

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  18 in total

1.  In Vivo Characterization of Dimethylsulfoniopropionate Lyase in the Fungus Fusarium lateritium.

Authors:  M K Bacic; D C Yoch
Journal:  Appl Environ Microbiol       Date:  1998-01       Impact factor: 4.792

2.  Effectors of the mammalian plasma membrane NADH-oxidoreductase system. Short-chain ubiquinone analogues as potent stimulators.

Authors:  F Vaillant; J A Larm; G L McMullen; E J Wolvetang; A Lawen
Journal:  J Bioenerg Biomembr       Date:  1996-12       Impact factor: 2.945

3.  Molecular mechanism of the inactivation of tryptophan hydroxylase by nitric oxide: attack on critical sulfhydryls that spare the enzyme iron center.

Authors:  D M Kuhn; R Arthur
Journal:  J Neurosci       Date:  1997-10-01       Impact factor: 6.167

4.  Oxidation and reduction of pig skeletal muscle ryanodine receptors.

Authors:  C S Haarmann; R H Fink; A F Dulhunty
Journal:  Biophys J       Date:  1999-12       Impact factor: 4.033

5.  Molecular characterization of the staphylococcal multidrug resistance export protein QacC.

Authors:  I T Paulsen; M H Brown; S J Dunstan; R A Skurray
Journal:  J Bacteriol       Date:  1995-05       Impact factor: 3.490

6.  Model of the exofacial substrate-binding site and helical folding of the human Glut1 glucose transporter based on scanning mutagenesis.

Authors:  Mike Mueckler; Carol Makepeace
Journal:  Biochemistry       Date:  2009-06-30       Impact factor: 3.162

7.  The role of cysteines and histidins of the norepinephrine transporter.

Authors:  Birger Wenge; Heinz Bönisch
Journal:  Neurochem Res       Date:  2013-03-23       Impact factor: 3.996

8.  Evidence for Intracellular and Extracellular Dimethylsulfoniopropionate (DMSP) Lyases and DMSP Uptake Sites in Two Species of Marine Bacteria.

Authors:  D C Yoch; J H Ansede; K S Rabinowitz
Journal:  Appl Environ Microbiol       Date:  1997-08       Impact factor: 4.792

9.  N-Ethylmaleimide differentially inhibits substrate uptake by and ligand binding to the noradrenaline transporter.

Authors:  Birger Wenge; Heinz Bönisch
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2008-03-21       Impact factor: 3.000

10.  Functional significance of a protein conformation change at the cytoplasmic end of helix F during the bacteriorhodopsin photocycle.

Authors:  L S Brown; G Váró; R Needleman; J K Lanyi
Journal:  Biophys J       Date:  1995-11       Impact factor: 4.033
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