Literature DB >> 15108776

Morbid obesity does not preclude successful renal transplantation.

William M Bennett1, Kevin M McEvoy, Karen R Henell, John F Valente, Viken Douzdjian.   

Abstract

Many renal transplantation centers arbitrarily deny transplantation to patients with morbid obesity usually defined as body mass index > 35. We present a series of 173 primary renal transplant patients in a new transplant program that accepted all recipients with 3 yrs or greater life expectancy and no active malignancy or infection. When the patient outcomes are divided into groups by body mass index, it can be seen as expected that patients with body mass index > 30 have an increased prevalence of wound infections (p < 0.05). However, aside from this complication there are no statistically significant outcome differences between the three groups realizing the possibility of type II statistical error because of small numbers. Graft survival, patient survival and other surgical complications are the same in all groups regardless of body mass index. At the end of the 3-yr interval with a minimum transplant follow-up of 3 months, 169 of 173 patients were alive and 163 of 173 transplants were functioning. Based on our experience, morbid obesity should not be used to exclude patients arbitrarily from transplantation anymore than advanced age or diabetes should.

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Year:  2004        PMID: 15108776

Source DB:  PubMed          Journal:  Clin Transplant        ISSN: 0902-0063            Impact factor:   2.863


  7 in total

Review 1.  Bariatric surgery and renal function.

Authors:  Andrew Currie; Andrew Chetwood; Ahmed R Ahmed
Journal:  Obes Surg       Date:  2011-04       Impact factor: 4.129

2.  Transplantation: does BMI sufficiently predict renal transplant outcomes?

Authors:  Josep M Grinyó
Journal:  Nat Rev Nephrol       Date:  2012-08-07       Impact factor: 28.314

3.  Associations of pretransplant weight and muscle mass with mortality in renal transplant recipients.

Authors:  Elani Streja; Miklos Z Molnar; Csaba P Kovesdy; Suphamai Bunnapradist; Jennie Jing; Allen R Nissenson; Istvan Mucsi; Gabriel M Danovitch; Kamyar Kalantar-Zadeh
Journal:  Clin J Am Soc Nephrol       Date:  2011-03-17       Impact factor: 8.237

4.  Higher recipient body mass index is associated with post-transplant delayed kidney graft function.

Authors:  Miklos Z Molnar; Csaba P Kovesdy; Istvan Mucsi; Suphamai Bunnapradist; Elani Streja; Mahesh Krishnan; Kamyar Kalantar-Zadeh
Journal:  Kidney Int       Date:  2011-04-27       Impact factor: 10.612

Review 5.  Nondiabetic consequences of obesity on kidney.

Authors:  Tarak Srivastava
Journal:  Pediatr Nephrol       Date:  2006-02-21       Impact factor: 3.714

6.  Management of obesity in kidney transplant candidates and recipients: A clinical practice guideline by the DESCARTES Working Group of ERA.

Authors:  Gabriel C Oniscu; Daniel Abramowicz; Davide Bolignano; Ilaria Gandolfini; Rachel Hellemans; Umberto Maggiore; Ionut Nistor; Stephen O'Neill; Mehmet Sukru Sever; Muguet Koobasi; Evi V Nagler
Journal:  Nephrol Dial Transplant       Date:  2021-12-24       Impact factor: 5.992

7.  Study of weight and body mass index on graft loss after transplant over 5 years of evolution.

Authors:  Antonio Liñán González; Raquel García Pérez; Juan Bravo Soto; Rafael Fernández Castillo
Journal:  Int J Med Sci       Date:  2020-08-27       Impact factor: 3.738

  7 in total

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