Literature DB >> 15107744

[Hypertrophic cardiomyopathy associated with oral corticosteroid therapy for palpebral hemangioma].

K Some Nina1, G Lorette, A Chantepie, C Villerette, L Machet.   

Abstract

INTRODUCTION: Systemic corticosteroid therapy is the usual treatment for hemangioma with vascular risk. Tolerance to such treatment is usually good. OBSERVATION: A two Month-old girl presented with a hemangioma of the lower right eyelid that had developed since she was 15 days old. Treatment with betamethasone at the dose of 0.3 mg/kg/day was prescribed because of the risk of alteration in sight. The treatment was highly effective. The discovery of a systolic cardiac murmur motivated a cardiac sonography that showed signs of an obstructive hypertrophic myocardiopathy. The progressive reduction of the corticosteroids led to the regression of this disease. DISCUSSION: The onset of a cardiomyopathy during systemic corticosteroid therapy has only been reported exceptionally in the literature. There is little known of the risks. When in doubt, clinical and sonographic monitoring is probably necessary. In the case of the appearance of a cardiac murmur, the sonography is crucial.

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Year:  2004        PMID: 15107744     DOI: 10.1016/s0151-9638(04)93589-2

Source DB:  PubMed          Journal:  Ann Dermatol Venereol        ISSN: 0151-9638            Impact factor:   0.777


  1 in total

1.  Hepatic haemangioma-prenatal imaging findings, complications and perinatal outcome in a case series.

Authors:  Stephanie Franchi-Abella; Gillaume Gorincour; Freddy Avni; Laurent Guibaud; Laurent Chevret; Danièle Pariente
Journal:  Pediatr Radiol       Date:  2011-09-18
  1 in total

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