Literature DB >> 1510659

Augmented expression of HSP72 protein in normal human fibroblasts irradiated with ultraviolet light.

K Suzuki1, M Watanabe.   

Abstract

Normal human fibroblasts synthesized heat shock protein (HSP) 72 constitutively and its expression was augmented 6 hours after UV irradiation. Maximum induction of HSP72 was obtained at 12 hours and HSP72 showed a punctuated distribution in nucleus. While unscheduled DNA synthesis was almost completed 12 hours after UV irradiation, the S phase fraction decreased immediately and recovered after 6 hours. Thus, HSP72 augmentation was occurred coincidentally with the recovery of S phase, and suggested that HSP72 had some function during the recovery of DNA replication inhibited after UV irradiation.

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Year:  1992        PMID： 1510659     DOI： 10.1016/s0006-291x(05)81541-4

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  6 in total

Review 1.  Chaperones in cell cycle regulation and mitogenic signal transduction: a review.

Authors:  K Helmbrecht; E Zeise; L Rensing
Journal:  Cell Prolif       Date:  2000-12       Impact factor: 6.831

2.  Heat shock and proinflammatory stressors induce differential localization of heat shock proteins in human monocytes.

Authors:  E Mariéthoz; M R Jacquier-Sarlin; G Multhoff; A M Healy; F Tacchini-Cottier; B S Polla
Journal:  Inflammation       Date:  1997-12       Impact factor: 4.092

3.  Retinoid- and sodium-butyrate-induced decrease in heat shock protein 70 membrane-positive tumor cells is associated with reduced sensitivity to natural killer cell lysis, growth delay, and altered growth morphology.

Authors:  Mathias Gehrmann; Johann Schönberger; Tanja Zilch; Lydia Rossbacher; Gerald Thonigs; Christoph Eilles; Gabriele Multhoff
Journal:  Cell Stress Chaperones       Date:  2005       Impact factor: 3.667

Review 4.  The therapeutic implications of clinically applied modifiers of heat shock protein 70 (Hsp70) expression by tumor cells.

Authors:  Mathias Gehrmann; Jürgen Radons; Michael Molls; Gabriele Multhoff
Journal:  Cell Stress Chaperones       Date:  2008-02-05       Impact factor: 3.667

5.  Amniotic fluid heat shock protein 70 concentration in histologic chorioamnionitis, term and preterm parturition.

Authors:  Tinnakorn Chaiworapongsa; Offer Erez; Juan Pedro Kusanovic; Edi Vaisbuch; Shali Mazaki-Tovi; Francesca Gotsch; Nandor Gabor Than; Pooja Mittal; Yeon Mee Kim; Natalia Camacho; Samuel Edwin; Ricardo Gomez; Sonia S Hassan; Roberto Romero
Journal:  J Matern Fetal Neonatal Med       Date:  2008-07

Review 6.  Membrane-Associated Heat Shock Proteins in Oncology: From Basic Research to New Theranostic Targets.

Authors:  Maxim Shevtsov; Zsolt Balogi; William Khachatryan; Huile Gao; László Vígh; Gabriele Multhoff
Journal:  Cells       Date:  2020-05-20       Impact factor: 6.600
  6 in total

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