Literature DB >> 1510657

Reactive oxygen-reducing and protein-refolding activities of adult T cell leukemia-derived factor/human thioredoxin.

A Mitsui1, T Hirakawa, J Yodoi.   

Abstract

Reducing and protein-refolding activities of adult T cell leukemia-derived factor (ADF)/human thioredoxin were studied. Recombinant ADF/human thioredoxin produced by E. coli, which has an insulin-reducing activity as efficient as that of E. coli thioredoxin, also reduced some reactive oxygen species, such as hydrogen peroxide. Furthermore, recombinant ADF/human thioredoxin was found to have protein-refolding activity for scrambled (mispaired disulfide-containing) RNase A. Cys-31 at the active site of ADF/human thioredoxin proved essential for reducing activity, and loss of Cys-31 in ADF/human thioredoxin attenuated the protein-refolding activity. These data suggest a physiological role of ADF/human thioredoxin in protecting living cells from proteotoxicity caused by reactive oxygens in vivo.

Entities:  

Mesh：

Substances：

Year:  1992        PMID： 1510657     DOI： 10.1016/s0006-291x(05)81536-0

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  35 in total

1.  Attenuation of indomethacin-induced gastric mucosal injury by prophylactic administration of sake yeast-derived thioredoxin.

Authors:  Atsushi Nakajima; Toshiro Fukui; Yu Takahashi; Masanobu Kishimoto; Masao Yamashina; Shinji Nakayama; Yutaku Sakaguchi; Katsunori Yoshida; Kazushige Uchida; Akiyoshi Nishio; Junji Yodoi; Kazuichi Okazaki
Journal:  J Gastroenterol       Date:  2012-03-09       Impact factor: 7.527

2.  Redox systems of the cell: possible links and implications.

Authors:  Kumuda C Das; Carl W White
Journal:  Proc Natl Acad Sci U S A       Date:  2002-07-16       Impact factor: 11.205

3.  Effects of oxalate exposure on Madin-Darby canine kidney cells in culture: renal prothrombin fragment-1 mRNA expression.

Authors:  Manabu T Moryama; Chizue Domiki; Katsuhito Miyazawa; Tatsuro Tanaka; Koji Suzuki
Journal:  Urol Res       Date:  2005-12-01

4.  Regulation of the fission yeast transcription factor Pap1 by oxidative stress: requirement for the nuclear export factor Crm1 (Exportin) and the stress-activated MAP kinase Sty1/Spc1.

Authors:  W M Toone; S Kuge; M Samuels; B A Morgan; T Toda; N Jones
Journal:  Genes Dev       Date:  1998-05-15       Impact factor: 11.361

5.  A crucial role for thiol antioxidants in estrogen-deficiency bone loss.

Authors:  Jenny M Lean; Julie T Davies; Karen Fuller; Christopher J Jagger; Barrie Kirstein; Geoffrey A Partington; Zoë L Urry; Timothy J Chambers
Journal:  J Clin Invest       Date:  2003-09       Impact factor: 14.808

6.  Suppressive effect of administration of recombinant human thioredoxin on cutaneous  inflammation caused by UV.

Authors:  Ryusuke Ono; Atsushi Fukunaga; Taro Masaki; Xijun Yu; Junji Yodoi; Chikako Nishigori
Journal:  Bioengineered       Date:  2013-01-17       Impact factor: 3.269

7.  Expression of the adult T-cell leukemia-derived factor, human thioredoxin, in the allotransplanted canine lung.

Authors:  K Muro; T Go; T Hirata; T Fukuse; H Yokomise; K Inui; J Yodoi; S Hitomi; H Wada
Journal:  Surg Today       Date:  1995       Impact factor: 2.549

8.  Identification and functional characterization of thioredoxin of Mycobacterium tuberculosis.

Authors:  B Wieles; S Nagai; H G Wiker; M Harboe; T H Ottenhoff
Journal:  Infect Immun       Date:  1995-12       Impact factor: 3.441

9.  Redox responses in patients with sepsis: high correlation of thioredoxin-1 and macrophage migration inhibitory factor plasma levels.

Authors:  Thorsten Brenner; Claudia Rosenhagen; Jochen Steppan; Christoph Lichtenstern; Jürgen Weitz; Thomas Bruckner; Eike O Martin; Ursula Hoffmann; Markus A Weigand; Stefan Hofer
Journal:  Mediators Inflamm       Date:  2010-08-05       Impact factor: 4.711

10.  Thioredoxins in redox maintenance and survival during oxidative stress of Bacteroides fragilis.

Authors:  Michael A Reott; Anita C Parker; Edson R Rocha; C Jeffrey Smith
Journal:  J Bacteriol       Date:  2009-03-13       Impact factor: 3.490
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.