Literature DB >> 15105281

Cardiovascular biology of the asymmetric dimethylarginine:dimethylarginine dimethylaminohydrolase pathway.

Patrick Vallance1, James Leiper.   

Abstract

An increasing number of reports indicate that endogenously produced inhibitors of nitric oxide synthase, particularly asymmetric dimethylarginine (ADMA), regulate nitric oxide generation in disease states. This article describes the biology of ADMA and the implications for cardiovascular physiology and pathophysiology.

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Year:  2004        PMID: 15105281     DOI: 10.1161/01.ATV.0000128897.54893.26

Source DB:  PubMed          Journal:  Arterioscler Thromb Vasc Biol        ISSN: 1079-5642            Impact factor:   8.311


  132 in total

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Review 2.  Small Molecule Inhibitors of Protein Arginine Methyltransferases.

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Review 3.  Genetic regulation of endothelial function.

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Journal:  Heart       Date:  2005-10       Impact factor: 5.994

4.  Identification of small-molecule enhancers of arginine methylation catalyzed by coactivator-associated arginine methyltransferase 1.

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Journal:  J Med Chem       Date:  2012-11-02       Impact factor: 7.446

5.  Redox Control of Protein Arginine Methyltransferase 1 (PRMT1) Activity.

Authors:  Yalemi Morales; Damon V Nitzel; Owen M Price; Shanying Gui; Jun Li; Jun Qu; Joan M Hevel
Journal:  J Biol Chem       Date:  2015-04-24       Impact factor: 5.157

6.  Asymmetric dimethylarginine induces endothelial nitric-oxide synthase mitochondrial redistribution through the nitration-mediated activation of Akt1.

Authors:  Ruslan Rafikov; Olga Rafikova; Saurabh Aggarwal; Christine Gross; Xutong Sun; Julin Desai; David Fulton; Stephen M Black
Journal:  J Biol Chem       Date:  2012-12-19       Impact factor: 5.157

7.  Human alanine-glyoxylate aminotransferase 2 lowers asymmetric dimethylarginine and protects from inhibition of nitric oxide production.

Authors:  Roman N Rodionov; Daryl J Murry; Sarah F Vaulman; Jeff W Stevens; Steven R Lentz
Journal:  J Biol Chem       Date:  2009-12-14       Impact factor: 5.157

8.  Tissue-specific downregulation of dimethylarginine dimethylaminohydrolase in hyperhomocysteinemia.

Authors:  Sanjana Dayal; Roman N Rodionov; Erland Arning; Teodoro Bottiglieri; Masumi Kimoto; Daryl J Murry; John P Cooke; Frank M Faraci; Steven R Lentz
Journal:  Am J Physiol Heart Circ Physiol       Date:  2008-06-20       Impact factor: 4.733

Review 9.  Extracellular matrix roles in cardiorenal fibrosis: Potential therapeutic targets for CVD and CKD in the elderly.

Authors:  Hiroe Toba; Merry L Lindsey
Journal:  Pharmacol Ther       Date:  2018-08-25       Impact factor: 12.310

10.  Coordinated regulation of dimethylarginine dimethylaminohydrolase-1 and cationic amino acid transporter-1 by farnesoid X receptor in mouse liver and kidney and its implication in the control of blood levels of asymmetric dimethylarginine.

Authors:  Jiang Li; Annette Wilson; Xiang Gao; Ramalinga Kuruba; Youhua Liu; Samuel Poloyac; Bruce Pitt; Wen Xie; Song Li
Journal:  J Pharmacol Exp Ther       Date:  2009-07-15       Impact factor: 4.030

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