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Literature DB >> 15105264

Redox metals in Alzheimer's disease.

Abstract

Redox metals in the brain play many important roles in maintenance of cellular function. The maintenance of their homeostasis is of paramount importance to a number of diseases such as Alzheimer's disease and multiple sclerosis. Iron, copper, and zinc are metals of special interest in the pathogenesis of these disorders. This review will focus primarily on iron.

Entities: Chemical Disease

Mesh：

Substances：

Year: 2004 PMID： 15105264 DOI： 10.1196/annals.1306.014

Source DB: PubMed Journal: Ann N Y Acad Sci ISSN： 0077-8923 Impact factor: 5.691

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Cited

16 in total

1. Deferiprone reduces amyloid-β and tau phosphorylation levels but not reactive oxygen species generation in hippocampus of rabbits fed a cholesterol-enriched diet.

Authors: Jaya R P Prasanthi; Matthew Schrag; Bhanu Dasari; Gurdeep Marwarha; April Dickson; Wolff M Kirsch; Othman Ghribi
Journal: J Alzheimers Dis Date: 2012 Impact factor: 4.472

2. Early post-natal iron administration induces astroglial response in the brain of adult and aged rats.

Authors: Liana Lisboa Fernandez; Maria Noêmia Martins de Lima; Felipe Scalco; Gustavo Vedana; Clívia Miwa; Arlete Hilbig; Mônica Vianna; Nadja Schröder
Journal: Neurotox Res Date: 2010-12-17 Impact factor: 3.911

3. Brain catalase in the streptozotocin-rat model of sporadic Alzheimer's disease treated with the iron chelator-monoamine oxidase inhibitor, M30.

Authors: E Sofic; M Salkovic-Petrisic; I Tahirovic; A Sapcanin; S Mandel; M Youdim; P Riederer
Journal: J Neural Transm (Vienna) Date: 2014-09-25 Impact factor: 3.575

4. Cumulative lead exposure is associated with reduced olfactory recognition performance in elderly men: The Normative Aging Study.

Authors: Rachel Grashow; David Sparrow; Howard Hu; Marc G Weisskopf
Journal: Neurotoxicology Date: 2015-06-26 Impact factor: 4.294

10. Silencing GADD153/CHOP gene expression protects against Alzheimer's disease-like pathology induced by 27-hydroxycholesterol in rabbit hippocampus.

Authors: Jaya R P Prasanthi; Tyler Larson; Jared Schommer; Othman Ghribi
Journal: PLoS One Date: 2011-10-14 Impact factor: 3.240

Redox metals in Alzheimer's disease.

1. Deferiprone reduces amyloid-β and tau phosphorylation levels but not reactive oxygen species generation in hippocampus of rabbits fed a cholesterol-enriched diet.

2. Early post-natal iron administration induces astroglial response in the brain of adult and aged rats.

3. Brain catalase in the streptozotocin-rat model of sporadic Alzheimer's disease treated with the iron chelator-monoamine oxidase inhibitor, M30.

4. Cumulative lead exposure is associated with reduced olfactory recognition performance in elderly men: The Normative Aging Study.

5. Histological co-localization of iron in Abeta plaques of PS/APP transgenic mice.

Review 6. Towards the prevention of potential aluminum toxic effects and an effective treatment for Alzheimer's disease.

7. Regional dissection and determination of loosely bound and non-heme iron in the developing mouse brain.

8. Mutual stimulation of beta-amyloid fibrillogenesis by clioquinol and divalent metals.

Review 9. Pharmacokinetics, pharmacodynamics and toxicology of theranostic nanoparticles.

10. Silencing GADD153/CHOP gene expression protects against Alzheimer's disease-like pathology induced by 27-hydroxycholesterol in rabbit hippocampus.