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Literature DB >> 15105152

Development of a liposome formulation of ethambutol.

Theresa Wiens¹, Thomas Redelmeier, Yossef Av-Gay.

Abstract

A liposomal formulation capable of encapsulating 76 to 92% of the antimycobacterial drug ethambutol and showing prolonged in vitro release kinetics is described. In vitro efficacy is equivalent to that of the free drug, suggesting that encapsulation of ethambutol has the potential to shorten the current regimens for tuberculosis.

Entities: Chemical Disease

Mesh：

Substances：

Year: 2004 PMID： 15105152 PMCID： PMC400583 DOI： 10.1128/AAC.48.5.1887-1888.2004

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

11 in total

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Journal: Antimicrob Agents Chemother Date: 1992-12 Impact factor: 5.191

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Journal: Immunobiology Date: 1994-10 Impact factor: 3.144

8. Pharmacokinetic comparison of intravenous carbendazim and remote loaded carbendazim liposomes in nude mice.

Authors: Lee Jia; Mark Garza; Hong Wong; Dody Reimer; Thomas Redelmeier; Jim B Camden; Steve D Weitman
Journal: J Pharm Biomed Anal Date: 2002-04-01 Impact factor: 3.935

9. Pharmacokinetics of ethambutol under fasting conditions, with food, and with antacids.

Authors: C A Peloquin; A E Bulpitt; G S Jaresko; R W Jelliffe; J M Childs; D E Nix
Journal: Antimicrob Agents Chemother Date: 1999-03 Impact factor: 5.191

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Journal: Chem Phys Lipids Date: 1986 Jun-Jul Impact factor: 3.329

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Review 4. Nanocarrier-Based Approaches for the Efficient Delivery of Anti-Tubercular Drugs and Vaccines for Management of Tuberculosis.

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